A protein interaction landscape of breast cancer

M Kim, J Park, M Bouhaddou, K Kim, A Rojc, M Modak… - Science, 2021 - science.org
INTRODUCTION Advances in DNA sequencing technology have enabled the widespread
analysis of breast tumor genomes, creating a catalog of genetic mutations that may initiate or …

[HTML][HTML] The role of polycomb group protein BMI1 in DNA repair and genomic stability

A Fitieh, AJ Locke, M Motamedi, IH Ismail - International Journal of …, 2021 - mdpi.com
The polycomb group (PcG) proteins are a class of transcriptional repressors that mediate
gene silencing through histone post-translational modifications. They are involved in the …

[HTML][HTML] Non-coding RNAs in normal B-cell development and in mantle cell lymphoma: from molecular mechanism to biomarker and therapeutic agent potential

O Kersy, M Salmon-Divon, O Shpilberg… - International Journal of …, 2021 - mdpi.com
B-lymphocytes are essential for an efficient immune response against a variety of
pathogens. A large fraction of hematologic malignancies are of B-cell origin, suggesting that …

[HTML][HTML] Comparative evaluation of BMI-1 proto-oncogene expression in normal tissue, adenoma and papillary carcinoma of human thyroid in pathology samples

M Hajian, A Esmaeili, A Talebi - BMC Research Notes, 2021 - Springer
Abstract Objective Papillary Thyroid carcinoma accounts for more than 60% of adult thyroid
carcinomas. Finding a helpful marker is vital to determine the correct treatment approach …

Methods and compositions for the treatment of cancer

J Lieberman, A Gilboa-geffen, LA Wheeler - US Patent 11,180,762, 2021 - Google Patents
US11180762B2 - Methods and compositions for the treatment of cancer - Google Patents
US11180762B2 - Methods and compositions for the treatment of cancer - Google Patents …

BMI1 is a Novel, Preclinical Target in Fusion-Positive Rhabdomyosarcoma

CE Shields - 2021 - search.proquest.com
Rhabdomyosarcoma (RMS) is a rare, understudied pediatric cancer. There are two main
types of RMS: fusion-negative rhabdomyosarcoma (FN-RMS) and fusion-positive …