Advances of peptides for antibacterial applications

Y Yan, Y Li, Z Zhang, X Wang, Y Niu, S Zhang… - Colloids and Surfaces B …, 2021 - Elsevier
In the past few decades, peptide antibacterial products with unique antibacterial
mechanisms have attracted widespread interest. They can effectively reduce the probability …

Recent advances in design of antimicrobial peptides and polypeptides toward clinical translation

Y Jiang, Y Chen, Z Song, Z Tan, J Cheng - Advanced Drug Delivery …, 2021 - Elsevier
The recent outbreaks of infectious diseases caused by multidrug-resistant pathogens have
sounded a piercing alarm for the need of new effective antimicrobial agents to guard public …

Computational methods and tools in antimicrobial peptide research

PGA Aronica, LM Reid, N Desai, J Li… - Journal of Chemical …, 2021 - ACS Publications
The evolution of antibiotic-resistant bacteria is an ongoing and troubling development that
has increased the number of diseases and infections that risk going untreated. There is an …

Physicochemical Features and Peculiarities of Interaction of AMP with the Membrane

M Pirtskhalava, B Vishnepolsky, M Grigolava… - Pharmaceuticals, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are anti-infectives that have the potential to be used as a
novel and untapped class of biotherapeutics. Modes of action of antimicrobial peptides …

Natural peptides inducing cancer cell death: Mechanisms and properties of specific candidates for cancer therapeutics

PA Trinidad-Calderón, CD Varela-Chinchilla… - Molecules, 2021 - mdpi.com
Nowadays, cancer has become the second highest leading cause of death, and it is
expected to continue to affect the population in forthcoming years. Additionally, treatment …

Molecular insights into pore formation mechanism, membrane perturbation, and water permeation by the antimicrobial peptide pleurocidin: a combined all-atom and …

R Talandashti, F Mehrnejad… - The Journal of …, 2021 - ACS Publications
The antimicrobial peptide (AMP) pleurocidin has a broad antimicrobial activity against Gram-
negative and Gram-positive bacteria by perturbation and permeabilizing their membranes; …

[HTML][HTML] Investigation of antibiofilm activity, antibacterial activity, and mechanistic studies of an amphiphilic peptide against Acinetobacter baumannii

P Zeng, L Yi, J Xu, W Gao, C Xu, S Chen… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Biofilm-producing pathogens, such as Acinetobacter baumannii, have aroused escalating
attention. Because these bacteria could secrete mixture with close-knit architecture and …

De novo designed phenol-soluble-modulins-inspired peptides as effective antimicrobial agents

P Zeng - 2021 - theses.lib.polyu.edu.hk
Human health is currently facing a serious threat from bacterial pathogens. In particular, the
aggravating clinical problems due to antimicrobial resistance call for alternative routes of …