[HTML][HTML] Unraveling the multifaceted nature of the nuclear function of mTOR

AS Torres, MK Holz - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2021 - Elsevier
Positioned at the axis between the cell and its environment, mTOR directs a wide range of
cellular activity in response to nutrients, growth factors, and stress. Our understanding of the …

CCL2 regulation of MST1-mTOR-STAT1 signaling axis controls BCR signaling and B-cell differentiation

L Yang, N Li, D Yang, A Chen, J Tang, Y Jing… - Cell Death & …, 2021 - nature.com
Chemokines are important regulators of the immune system, inducing specific cellular
responses by binding to receptors on immune cells. In SLE patients, decreased expression …

[HTML][HTML] mTOR regulates PRMT1 expression and mitochondrial mass through STAT1 phosphorylation in hepatic cell

X Zhang, L Li, Y Li, Z Li, W Zhai, Q Sun, X Yang… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Background Fasting changes mitochondrial function, and mTOR acts as a major regulator of
mitochondrial energy production ensuring the survival under reduced supply of nutrition …

mTOR inhibition promotes pneumonitis through inducing endothelial contraction and hyperpermeability

X Chen, C Hu, X Fan, Y Wang, Q Li, YQ Su… - American Journal of …, 2021 - atsjournals.org
Compromised endothelial-cell (EC) barrier function is a hallmark of inflammatory diseases.
mTOR inhibitors, widely applied as clinical therapies, cause pneumonitis through …

L-Leucine Promotes STAT1 and ISGs Expression in TGEV-Infected IPEC-J2 Cells via mTOR Activation

J Du, D Chen, B Yu, J He, J Yu, X Mao, Y Luo… - Frontiers in …, 2021 - frontiersin.org
L-leucine (Leu), as one of the effective amino acids to activate the mTOR signaling pathway,
can alleviate transmissible gastroenteritis virus (TGEV) infection. However, the underlying …

TRPC1‐mediated Ca2+ signaling enhances intestinal epithelial restitution by increasing α4 association with PP2Ac after wounding

N Rathor, HK Chung, JL Song, SR Wang… - Physiological …, 2021 - Wiley Online Library
Gut epithelial restitution after superficial wounding is an important repair modality regulated
by numerous factors including Ca2+ signaling and cellular polyamines. Transient receptor …

High-throughput evaluation of metabolic activities using reverse phase protein array technology

HY Lu, J Xiong, DN Perera, K Rajapakshe… - Neuron Signaling in …, 2021 - taylorfrancis.com
Reverse Phase Protein Array (RPPA) technology is a high-throughput proteomics platform
capable of reliably assaying thousands of samples at the same time for hundreds of …

12 Sex Differences in Feeding Regulated

KN Krolick, DN Tapp, MS McMurray… - Neuron Signaling in …, 2021 - books.google.com
12 Sex Differences in Feeding Regulated Page 262 12 Sex Differences in Feeding Regulated
by Estrogen Crosstalk between Dopaminergic Reward Circuitry and Adiposity Signals Kristen N …