COVID-19 vaccines: The status and perspectives in delivery points of view
Due to the high prevalence and long incubation periods often without symptoms, the severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected millions of individuals …
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected millions of individuals …
Phage display technique as a tool for diagnosis and antibody selection for coronaviruses
T Anand, N Virmani, BC Bera, RK Vaid, M Vashisth… - Current …, 2021 - Springer
Phage display is one of the important and effective molecular biology techniques and has
remained indispensable for research community since its discovery in the year 1985. As a …
remained indispensable for research community since its discovery in the year 1985. As a …
Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study
Abstract Coronavirus disease 2019 (COVID-19) antiviral response in a pan-tumor immune
monitoring (CAPTURE)(NCT03226886) is a prospective cohort study of COVID-19 immunity …
monitoring (CAPTURE)(NCT03226886) is a prospective cohort study of COVID-19 immunity …
CoV-AbDab: the coronavirus antibody database
MIJ Raybould, A Kovaltsuk, C Marks… - Bioinformatics, 2021 - academic.oup.com
Motivation The emergence of a novel strain of betacoronavirus, SARS-CoV-2, has led to a
pandemic that has been associated with over 700 000 deaths as of August 5, 2020 …
pandemic that has been associated with over 700 000 deaths as of August 5, 2020 …
Neutralizing antibody activity in convalescent sera from infection in humans with SARS-CoV-2 and variants of concern
COVID-19 vaccine design and vaccination rollout need to take into account a detailed
understanding of antibody durability and cross-neutralizing potential against SARS-CoV-2 …
understanding of antibody durability and cross-neutralizing potential against SARS-CoV-2 …
SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity
The coronaviral spike is the dominant viral antigen and the target of neutralizing antibodies.
We show that SARS-CoV-2 spike binds biliverdin and bilirubin, the tetrapyrrole products of …
We show that SARS-CoV-2 spike binds biliverdin and bilirubin, the tetrapyrrole products of …
Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection
H Yao, Y Sun, YQ Deng, N Wang, Y Tan, NN Zhang… - Cell research, 2021 - nature.com
Structural principles underlying the composition and synergistic mechanisms of protective
monoclonal antibody cocktails are poorly defined. Here, we exploited antibody cooperativity …
monoclonal antibody cocktails are poorly defined. Here, we exploited antibody cooperativity …
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease
SARS-CoV-2 is a coronavirus that emerged in 2019 and rapidly spread across the world
causing a deadly pandemic with tremendous social and economic costs. Healthcare …
causing a deadly pandemic with tremendous social and economic costs. Healthcare …
Targeting the conserved stem loop 2 motif in the SARS-CoV-2 genome
ABSTRACT RNA structural elements occur in numerous single-stranded positive-sense
RNA viruses. The stem-loop 2 motif (s2m) is one such element with an unusually high …
RNA viruses. The stem-loop 2 motif (s2m) is one such element with an unusually high …
Identification of 22 N-glycosites on spike glycoprotein of SARS-CoV-2 and accessible surface glycopeptide motifs: Implications for vaccination and antibody …
Coronaviruses hijack human enzymes to assemble the sugar coat on their spike
glycoproteins. The mechanisms by which human antibodies may recognize the antigenic …
glycoproteins. The mechanisms by which human antibodies may recognize the antigenic …