The effects of chronic exposure to ambient traffic-related air pollution on Alzheimer's disease phenotypes in wildtype and genetically predisposed male and female …
KT Patten, AE Valenzuela, C Wallis… - Environmental …, 2021 - ehp.niehs.nih.gov
Background: Epidemiological data link traffic-related air pollution (TRAP) to increased risk of
Alzheimer's disease (AD). Preclinical data corroborating this association are largely from …
Alzheimer's disease (AD). Preclinical data corroborating this association are largely from …
Berberine Reduces Aβ42 Deposition and Tau Hyperphosphorylation via Ameliorating Endoplasmic Reticulum Stress
Y Wu, Q Chen, B Wen, N Wu, B He… - Frontiers in …, 2021 - frontiersin.org
Alzheimer's disease (AD) is tightly related to endoplasmic reticulum stress (ER stress), which
aggravates two dominant pathological manifestations of AD: senile plaques and …
aggravates two dominant pathological manifestations of AD: senile plaques and …
Dieckol ameliorates Aβ production via PI3K/Akt/GSK-3β regulated APP processing in SweAPP N2a cell
The proteolytic processing of amyloid precursor protein (APP) by β-secretase (BACE1) and γ-
secretase releases amyloid-β peptide (Aβ), which deposits in amyloid plaques and …
secretase releases amyloid-β peptide (Aβ), which deposits in amyloid plaques and …
NFL strongly correlates with TNF-R1 in the plasma of AD patients, but not with cognitive decline
Peripheral inflammation mechanisms involved in Alzheimer's disease (AD) have yet to be
accurately characterized and the identification of blood biomarker profiles could help predict …
accurately characterized and the identification of blood biomarker profiles could help predict …
Examining the effects of ovarian hormone loss and diet-induced obesity on alzheimer's disease markers of amyloid-β production and degradation
GC Hayward, BJ Baranowski… - Journal of …, 2021 - journals.physiology.org
After menopause, women experience declines in ovarian sex hormones, an event that has
recently been associated with increased amyloid-β peptides, a main feature of Alzheimer's …
recently been associated with increased amyloid-β peptides, a main feature of Alzheimer's …
Role of Hypoxia Inducible Factor (HIF) 1 α in Thiamine Insufficiency Mediated Alzheimer Disease Like Pathology
ML Valle - 2021 - search.proquest.com
Insufficiencies of the micronutrient thiamine (Vitamin B1) have been associated with
inducing Alzheimer's Disease (AD)-like neuropathology. Thiamine is a critical enzyme …
inducing Alzheimer's Disease (AD)-like neuropathology. Thiamine is a critical enzyme …