The emergence and spread of infectious diseases with pandemic potential occurred
regularly throughout history. Major pandemics and epidemics such as plague, cholera, flu …

Abstract Coronavirus disease 2019 (COVID-19) is the second pandemic of the twenty-first
century, with over one-hundred million infections and over two million deaths to date. It is a …

Background The efficacy and safety of tofacitinib, a Janus kinase inhibitor, in patients who
are hospitalized with coronavirus disease 2019 (Covid-19) pneumonia are unclear. Methods …

Purpose Corticosteroids are now recommended for patients with severe COVID-19 including
those with COVID-related ARDS. This has generated renewed interest regarding whether …

Background Monoclonal antibodies (mAbs) are laboratory‐produced molecules derived
from the B cells of an infected host. They are being investigated as a potential therapy for …

The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has caused the
Coronavirus Disease 2019 (COVID-19) worldwide pandemic in 2020. In response, most …

Clinical question What is the role of drugs in preventing covid-19? Why does this matter?
There is widespread interest in whether drug interventions can be used for the prevention of …

Updates This is the second version (first update) of the living systematic review, replacing
the previous version (available as a data supplement). When citing this paper please …

Context. Calcifediol has been proposed as a potential treatment for COVID-19 patients.
Objective: To compare the administration or not of oral calcifediol on mortality risk of patients …

Infection with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) results in
diverse outcomes. The symptoms appear to be more severe in males older than 65 and …