Cancer immunotherapy has revolutionised cancer treatment, with immune checkpoint
blockade (ICB) therapy and adoptive cell therapy (ACT) increasingly becoming standard of …

Simple Summary In the fight against cancer, immunotherapies have given great hope after
encouraging results in clinical investigations showing complete remission in some patients …

Radiation therapy can potentially induce immunogenic cell death, thereby priming anti-
tumor adaptive immune responses. However, radiation-induced systemic immune …

The tumor microenvironment (TME) is a complex ecosystem, which includes many different
types of cells, abnormal vascular systems, and immunosuppressive cytokines. TME serves …

Bacterial outer membrane vesicles (OMV) have gained attention as a promising new cancer
vaccine platform for efficiently provoking immune responses. However, OMV induce severe …

The mechanism by which anti-cancer immunity shapes early carcinogenesis of lung
adenocarcinoma (ADC) is unknown. In this study, we characterize the immune contexture of …

In the tumor microenvironment, T cells, B cells, and many other cells play important and
distinct roles in anti‐tumor immunotherapy. Although the immune checkpoint blockade and …

The combination of immunotherapy with other forms of treatment is an emerging strategy for
boosting antitumor responses. By combining multiple modes of action, these combinatorial …

Clinical studies in a range of cancers have detected elevated levels of the Wnt antagonist
Dickkopf-1 (DKK1) in the serum or tumors of patients, and this was frequently associated …

Despite developments in the treatment of various cancers, prostate cancer is one of the
deadliest diseases known to men. Systemic therapies such as androgen deprivation …