The complex link between NAFLD and type 2 diabetes mellitus—mechanisms and treatments
Nonalcoholic fatty liver disease (NAFLD) has reached epidemic proportions worldwide.
NAFLD and type 2 diabetes mellitus (T2DM) are known to frequently coexist and act …
NAFLD and type 2 diabetes mellitus (T2DM) are known to frequently coexist and act …
Non-alcoholic fatty liver disease and risk of fatal and non-fatal cardiovascular events: an updated systematic review and meta-analysis
A Mantovani, A Csermely, G Petracca… - The lancet …, 2021 - thelancet.com
Background Studies have reported a significant association between non-alcoholic fatty liver
disease (NAFLD) and increased incidence of cardiovascular disease (CVD). However, the …
disease (NAFLD) and increased incidence of cardiovascular disease (CVD). However, the …
The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis
TP Fidler, C Xue, M Yalcinkaya, B Hardaway… - Nature, 2021 - nature.com
Clonal haematopoiesis, which is highly prevalent in older individuals, arises from somatic
mutations that endow a proliferative advantage to haematopoietic cells. Clonal …
mutations that endow a proliferative advantage to haematopoietic cells. Clonal …
The power of genetic diversity in genome-wide association studies of lipids
Increased blood lipid levels are heritable risk factors of cardiovascular disease with varied
prevalence worldwide owing to different dietary patterns and medication use. Despite …
prevalence worldwide owing to different dietary patterns and medication use. Despite …
[HTML][HTML] Metabolic-associated fatty liver disease and lipoprotein metabolism
J Heeren, L Scheja - Molecular metabolism, 2021 - Elsevier
Background Non-alcoholic fatty liver disease, or as recently proposed 'metabolic-associated
fatty liver disease'(MAFLD), is characterized by pathological accumulation of triglycerides …
fatty liver disease'(MAFLD), is characterized by pathological accumulation of triglycerides …
NAFLD and cardiovascular diseases: a clinical review
P Kasper, A Martin, S Lang, F Kuetting… - Clinical research in …, 2021 - Springer
Non-alcoholic fatty liver DISEASE (NAFLD) is the most common chronic liver disease in
Western countries and affects approximately 25% of the adult population. Since NAFLD is …
Western countries and affects approximately 25% of the adult population. Since NAFLD is …
Genetics of 35 blood and urine biomarkers in the UK Biobank
Clinical laboratory tests are a critical component of the continuum of care. We evaluate the
genetic basis of 35 blood and urine laboratory measurements in the UK Biobank (n …
genetic basis of 35 blood and urine laboratory measurements in the UK Biobank (n …
Systems biology in cardiovascular disease: a multiomics approach
Omics techniques generate large, multidimensional data that are amenable to analysis by
new informatics approaches alongside conventional statistical methods. Systems theories …
new informatics approaches alongside conventional statistical methods. Systems theories …
Nonalcoholic fatty liver disease as a metabolic disease in humans: A literature review
Aims To conduct a systematic literature review to identify recent epidemiological, biomarker,
genetic and clinical evidence that expands our understanding of nonalcoholic fatty liver …
genetic and clinical evidence that expands our understanding of nonalcoholic fatty liver …
Clonal hematopoiesis of indeterminate potential (CHIP): Linking somatic mutations, hematopoiesis, chronic inflammation and cardiovascular disease
Clonal hematopoiesis of indeterminate potential (CHIP) is the presence of a clonally
expanded hematopoietic stem cell caused by a leukemogenic mutation in individuals …
expanded hematopoietic stem cell caused by a leukemogenic mutation in individuals …