EAU-EANM-ESTRO-ESUR-SIOG guidelines on prostate cancer—2020 update. Part 1: screening, diagnosis, and local treatment with curative intent

N Mottet, RCN van den Bergh, E Briers… - European urology, 2021 - Elsevier
Objective To present a summary of the 2020 version of the European Association of Urology
(EAU)-European Association of Nuclear Medicine (EANM)-European Society for …

Epidemiology and genomics of prostate cancer in Asian men

Y Zhu, M Mo, Y Wei, J Wu, J Pan, SJ Freedland… - Nature Reviews …, 2021 - nature.com
Prostate cancer is a global health problem, but incidence varies considerably across
different continents. Asia is traditionally considered a low-incidence area, but the incidence …

[HTML][HTML] MRI-targeted or standard biopsy in prostate cancer screening

M Eklund, F Jäderling, A Discacciati… - New England journal …, 2021 - Mass Medical Soc
Background High rates of overdiagnosis are a critical barrier to organized prostate cancer
screening. Magnetic resonance imaging (MRI) with targeted biopsy has shown the potential …

Cancer survival statistics for patients and healthcare professionals–a tutorial of real‐world data analysis

S Eloranta, KE Smedby, PW Dickman… - Journal of internal …, 2021 - Wiley Online Library
Monitoring survival of cancer patients using data collected by population‐based cancer
registries is an important component of cancer control. In this setting, patient survival is often …

A prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT): initial results from an international …

EK Bancroft, EC Page, MN Brook, S Thomas… - The Lancet …, 2021 - thelancet.com
Background Lynch syndrome is a rare familial cancer syndrome caused by pathogenic
variants in the mismatch repair genes MLH1, MSH2, MSH6, or PMS2, that cause …

Plasmatic exosome number and size distinguish prostate cancer patients from healthy individuals: A prospective clinical study

M Logozzi, D Mizzoni, R Di Raimo, A Giuliani… - Frontiers in …, 2021 - frontiersin.org
There is a urgent need for valuable strategy in early and less invasive diagnosis for cancer.
Preliminary data have shown that the plasmatic levels of exosomes increase in cancer …

Identification and validation of a prognostic signature for prostate cancer based on ferroptosis-related genes

H Liu, L Gao, T Xie, J Li, T Zhai, Y Xu - Frontiers in oncology, 2021 - frontiersin.org
Ferroptosis, an iron-dependent form of selective cell death, is involved in the development of
many cancers. However, ferroptosis related genes (FRGs) in prostate cancer (PCa) are not …

Circulating tumor DNA (ctDNA) as a pan-cancer screening test: is it finally on the horizon?

MJ Duffy, EP Diamandis, J Crown - Clinical Chemistry and …, 2021 - degruyter.com
The detection of cancer at an early stage while it is curable by surgical resection is widely
believed to be one of the most effective strategies for reducing cancer mortality. Hence, the …

Benefit, harm, and cost-effectiveness associated with magnetic resonance imaging before biopsy in age-based and risk-stratified screening for prostate cancer

T Callender, M Emberton, S Morris… - JAMA Network …, 2021 - jamanetwork.com
Importance If magnetic resonance imaging (MRI) mitigates overdiagnosis of prostate cancer
while improving the detection of clinically significant cases, including MRI in a screening …

Polygenic risk-tailored screening for prostate cancer: A benefit–harm and cost-effectiveness modelling study

T Callender, M Emberton, S Morris… - Advances in …, 2021 - api.taylorfrancis.com
Screening with a prostate-specific antigen (PSA) test could reduce death from prostate
cancer in some men but at the cost of substantial numbers overdiagnosed, as well as false …