Progression of basal ganglia pathology in heterozygous Q175 knock‐in Huntington's disease mice
Y Deng, H Wang, M Joni, R Sekhri… - Journal of Comparative …, 2021 - Wiley Online Library
We used behavioral testing and morphological methods to detail the progression of basal
ganglia neuron type‐specific pathology and the deficits stemming from them in male …
ganglia neuron type‐specific pathology and the deficits stemming from them in male …
Huntington's disease brain-derived small RNAs recapitulate associated neuropathology in mice
J Creus-Muncunill, A Guisado-Corcoll, V Venturi… - Acta …, 2021 - Springer
Progressive motor alterations and selective death of striatal medium spiny neurons (MSNs)
are key pathological hallmarks of Huntington's disease (HD), a neurodegenerative condition …
are key pathological hallmarks of Huntington's disease (HD), a neurodegenerative condition …
Expression of FoxP2 in the basal ganglia regulates vocal motor sequences in the adult songbird
Disruption of the transcription factor FoxP2, which is enriched in the basal ganglia, impairs
vocal development in humans and songbirds. The basal ganglia are important for the …
vocal development in humans and songbirds. The basal ganglia are important for the …
[HTML][HTML] Combined treatment with C16 peptide and angiopoietin-1 confers neuroprotection and reduces inflammation in 3-nitropropionic acid-induced dystonia mice
XX Fu, HY Cai, H Jiang, S Han - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Dystonia is a disorder associated with abnormalities in many brain regions including the
basal ganglia and cerebellum. The toxin 3-Nitropropionic acid (3-NP) can induce …
basal ganglia and cerebellum. The toxin 3-Nitropropionic acid (3-NP) can induce …
Age-Dependent Degradation of Locomotion Encoding in Huntington's Disease R6/2 Model Mice
HG Yamin, N Menkes-Caspi, EA Stern… - Journal of …, 2021 - content.iospress.com
Background: Huntington's disease (HD) is an inherited fatal neurodegenerative disease,
leading to neocortical and striatal atrophy. The commonly studied R6/2 HD transgenic …
leading to neocortical and striatal atrophy. The commonly studied R6/2 HD transgenic …
Dysregulation of the basal ganglia indirect pathway prior to cell loss in the Q175 mouse model of Huntington's disease
JW Callahan, DL Wokosin, MD Bevan - BioRxiv, 2021 - biorxiv.org
The psychomotor symptoms of Huntington's disease (HD) are linked to degeneration of the
basal ganglia indirect pathway. To determine how this pathway is perturbed prior to cell loss …
basal ganglia indirect pathway. To determine how this pathway is perturbed prior to cell loss …
Huntington's disease brain-derived small RNAs recapitulate associated neuropathology in wild-type mice
J Creus Muncunill, A Guisado Corcoll… - … , 2021, vol. 141, num …, 2021 - diposit.ub.edu
Progressive motor alterations and selective death of striatal medium spiny neurons (MSNs)
are key pathological hallmarks of Huntington's disease (HD), a neurodegenerative condition …
are key pathological hallmarks of Huntington's disease (HD), a neurodegenerative condition …
Analysing the Contribution of SNARE-Dependent Exocytosis From Astrocytes to Huntinton's Disease Pathogenesis Using the BACHD Mouse Model
AC King - 2021 - digitalcommons.library.uab.edu
Huntington's disease (HD) is a dominantly inherited neurodegenerative disease caused by
a polyglutamine expansion in the huntingtin protein. Multiple studies have indicated the …
a polyglutamine expansion in the huntingtin protein. Multiple studies have indicated the …