Bench research informed by GWAS results

NV Kondratyev, MV Alfimova, AK Golov, VE Golimbet - Cells, 2021 - mdpi.com
Scientifically interesting as well as practically important phenotypes often belong to the
realm of complex traits. To the extent that these traits are hereditary, they are usually 'highly …

DPEP1 and CHMP1A in kidney ferroptosis

SJ Allison - Nature Reviews Nephrology, 2021 - nature.com
Pathological glomerular lipid accumulation can result from downregulation of phospholipid-
transporting ATPase ABCA1-dependent cholesterol efflux. Wright et al. found that exposure …

Bioinformatics analysis of differentially expressed genes in non alcoholic fatty liver disease using next generation sequencing data

B Vastrad, C Vastrad - bioRxiv, 2021 - biorxiv.org
Non alcoholic fatty liver disease (NAFLD) is the most common metabolic disease in humans,
affecting the majority of individuals. In the current investigation, we aim to identify potential …