Current concepts and advances in biomarkers of acute kidney injury

Y Wen, CR Parikh - Critical reviews in clinical laboratory sciences, 2021 - Taylor & Francis
Despite advancements in standardizing the criteria for acute kidney injury (AKI), its definition
remains based on changes in serum creatinine and urinary output that do not specifically …

Malaria-associated acute kidney injury in African children: prevalence, pathophysiology, impact, and management challenges

A Batte, Z Berrens, K Murphy, I Mufumba… - … of Nephrology and …, 2021 - Taylor & Francis
Acute kidney injury (AKI) is emerging as a complication of increasing clinical importance
associated with substantial morbidity and mortality in African children with severe malaria …

Left and right ventricular dysfunction in patients with COVID-19-associated myocardial injury

S Bieber, A Kraechan, JC Hellmuth, M Muenchhoff… - Infection, 2021 - Springer
Purpose SARS-COV-2 infection can develop into a multi-organ disease. Although
pathophysiological mechanisms of COVID-19-associated myocardial injury have been …

A review of specific biomarkers of chronic renal injury and their potential application in nonclinical safety assessment studies

LA Obert, SA Elmore, D Ennulat… - Toxicologic …, 2021 - journals.sagepub.com
A host of novel renal biomarkers have been developed over the past few decades which
have enhanced monitoring of renal disease and drug-induced kidney injury in both …

Serum indices based on creatinine and cystatin C predict mortality in patients with non-dialysis chronic kidney disease

YL Lin, IC Chang, HH Liou, CH Wang, YH Lai… - Scientific reports, 2021 - nature.com
Serum indices based on creatinine and cystatin C, including creatinine/cystatin C ratio
(Cr/CysC), ratio and difference of estimated glomerular filtration rate (eGFR) based on …

AACC guidance document on laboratory investigation of acute kidney injury

JM El-Khoury, MP Hoenig, GRD Jones… - The journal of …, 2021 - academic.oup.com
Background Acute kidney injury (AKI) is a sudden episode of kidney damage or failure
affecting up to 15% of hospitalized patients and is associated with serious short-and long …

Phenolic profile, safety assessment, and anti-inflammatory activity of Salvia verbenaca L.

N Righi, S Boumerfeg, A Deghima… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Salvia species are known to have anti-inflammatory
properties, and are traditionally used for healing purposes. Salvia verbenaca is an Algerian …

Scoping review of augmented renal clearance in critically ill pediatric patients

DH Rhoney, SA Metzger… - … : The Journal of Human …, 2021 - Wiley Online Library
Augmented renal clearance (ARC), a phenomenon of enhanced elimination of renal solutes,
has been described in adult critically ill patients, but little is known about the phenomenon in …

Angiotensin (1–12) in humans with normal blood pressure and primary hypertension

CM Ferrario, SR Iyer, JC Burnett Jr, S Ahmad… - …, 2021 - Am Heart Assoc
The importance of canonical versus noncanonical mechanisms for the generation of
angiotensins remains a major challenge that, in part, is heavily swayed by the relative …

Does artificial intelligence make clinical decision better? A review of artificial intelligence and machine learning in acute kidney injury prediction

TH Lee, JJ Chen, CT Cheng, CH Chang - Healthcare, 2021 - mdpi.com
Acute kidney injury (AKI) is a common complication of hospitalization that greatly and
negatively affects the short-term and long-term outcomes of patients. Current guidelines use …