Long‐COVID syndrome‐associated brain fog and chemofog: Luteolin to the rescue

TC Theoharides, C Cholevas, K Polyzoidis… - Biofactors, 2021 - Wiley Online Library
COVID‐19 leads to severe respiratory problems, but also to long‐COVID syndrome
associated primarily with cognitive dysfunction and fatigue. Long‐COVID syndrome …

Neuroprotective effects of flavone luteolin in neuroinflammation and neurotrauma

D Kempuraj, R Thangavel, DD Kempuraj… - Biofactors, 2021 - Wiley Online Library
Neuroinflammation leads to neurodegeneration, cognitive defects, and neurodegenerative
disorders. Neurotrauma/traumatic brain injury (TBI) can cause activation of glial cells …

Prognostic value of interleukin-18 and its association with other inflammatory markers and disease severity in COVID-19

H Satış, HS Özger, PA Yıldız, K Hızel, Ö Gulbahar… - Cytokine, 2021 - Elsevier
Background The effectual immune response is crucial to defeat viral infections. However,
exuberant immune response with features of macrophage activation syndrome (MAS) lead …

IL-6 and IL-10 as predictors of disease severity in COVID-19 patients: results from meta-analysis and regression

SK Dhar, K Vishnupriyan, S Damodar, S Gujar, M Das - Heliyon, 2021 - cell.com
Abstract Aims SARS-CoV-2, an infectious agent behind the ongoing COVID-19 pandemic,
induces high levels of cytokines such as IL-1, IL-2, IL-4, IL-6, IL-10, TNF-α, IFN-γ etc in …

Early corticosteroids are associated with lower mortality in critically ill patients with COVID-19: a cohort study

P Monedero, A Gea, P Castro, AM Candela-Toha… - Critical Care, 2021 - Springer
Background Critically ill patients with coronavirus disease 19 (COVID-19) have a high
fatality rate likely due to a dysregulated immune response. Corticosteroids could attenuate …

Candidate antiviral drugs for COVID-19 and their environmental implications: a comprehensive analysis

P Biswas, MM Hasan, D Dey… - … Science and Pollution …, 2021 - Springer
Abstract Emerging from Wuhan, China, SARS-CoV-2 is the new global threat that killed
millions of people, and many are still suffering. This pandemic has not only affected people …

Metabolic dysfunction and immunometabolism in COVID-19 pathophysiology and therapeutics

R Batabyal, N Freishtat, E Hill, M Rehman… - International Journal of …, 2021 - nature.com
The COVID-19 pandemic has emerged as a public health crisis and has placed a significant
burden on healthcare systems. Patients with underlying metabolic dysfunction, such as type …

Revisiting activity of some glucocorticoids as a potential inhibitor of SARS-CoV-2 main protease: theoretical study

AA Elmaaty, R Alnajjar, MIA Hamed, M Khattab… - RSC …, 2021 - pubs.rsc.org
The global breakout of COVID-19 and raised death toll has prompted scientists to develop
novel drugs capable of inhibiting SARS-CoV-2. Conducting studies on repurposing some …

[HTML][HTML] To stress or not to stress: Brain-behavior-immune interaction may weaken or promote the immune response to SARS-CoV-2

EMJ Peters, M Schedlowski, C Watzl, U Gimsa - Neurobiology of stress, 2021 - Elsevier
The COVID-19 pandemic continues to strongly affect people with health disadvantages,
creating a heavy burden on medical systems and societies worldwide. Research is growing …

Does inpatient hyperglycemia predict a worse outcome in COVID‐19 intensive care unit patients?

AR Saand, M Flores, T Kewan, S Alqaisi… - Journal of …, 2021 - Wiley Online Library
Background We undertook this study to evaluate the association between hyperglycemia
and outcomes in patients with coronavirus disease 2019 (COVID‐19) admitted to the …