Oxidative stress is a key modulator in the development of nonalcoholic fatty liver disease

Y Ma, G Lee, SY Heo, YS Roh - Antioxidants, 2021 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide, and scientific studies consistently report that NAFLD development can be …

Oxidative stress and pathogenesis in malaria

M Vasquez, M Zuniga, A Rodriguez - Frontiers in cellular and …, 2021 - frontiersin.org
Malaria is a highly inflammatory and oxidative disease. The production of reactive oxygen
species by host phagocytes is an essential component of the host response to Plasmodium …

Biological functions of type II toxin-antitoxin systems in bacteria

M Kamruzzaman, AY Wu, JR Iredell - Microorganisms, 2021 - mdpi.com
After the first discovery in the 1980s in F-plasmids as a plasmid maintenance system, a
myriad of toxin-antitoxin (TA) systems has been identified in bacterial chromosomes and …

Effect of reactive oxygen species on the endoplasmic reticulum and mitochondria during intracellular pathogen infection of mammalian cells

J Lee, CH Song - Antioxidants, 2021 - mdpi.com
Oxidative stress, particularly reactive oxygen species (ROS), are important for innate
immunity against pathogens. ROS directly attack pathogens, regulate and amplify immune …

Detection of oxidative stress induced by nanomaterials in cells—the roles of reactive oxygen species and glutathione

J Čapek, T Roušar - Molecules, 2021 - mdpi.com
The potential of nanomaterials use is huge, especially in fields such as medicine or industry.
Due to widespread use of nanomaterials, their cytotoxicity and involvement in cellular …

Polyphenols as antioxidants for extending food shelf-life and in the prevention of health diseases: encapsulation and interfacial phenomena

M Costa, Z Sezgin-Bayindir, S Losada-Barreiro… - Biomedicines, 2021 - mdpi.com
Toxicity caused by the exposure to human-made chemicals and environmental conditions
has become a major health concern because they may significantly increase the formation …

Noxic effects of polystyrene microparticles on murine macrophages and epithelial cells

J Rudolph, M Völkl, V Jérôme, T Scheibel, R Freitag - Scientific reports, 2021 - nature.com
Microplastic (MP) contamination has been identified as an ecological problem with an
increasing impact on everyday life. Yet, possible effects of MP at the cellular level are still …

Cross‐Talk between Oxidative Stress and m6A RNA Methylation in Cancer

B Yang, Q Chen - Oxidative Medicine and Cellular Longevity, 2021 - Wiley Online Library
Oxidative stress is a state of imbalance between oxidation and antioxidation. Excessive ROS
levels are an important factor in tumor development. Damage stimulation and excessive …

Interplay between reactive oxygen/reactive nitrogen species and metabolism in vascular biology and disease

M Ushio-Fukai, D Ash, S Nagarkoti… - Antioxidants & redox …, 2021 - liebertpub.com
Reactive oxygen species (ROS; eg., superoxide [O2•−] and hydrogen peroxide [H2O2]) and
reactive nitrogen species (RNS; eg., nitric oxide [NO•]) at the physiological level function as …

Selective FPR2 agonism promotes a proresolution macrophage phenotype and improves cardiac structure-function post myocardial infarction

RA García, JA Lupisella, BR Ito, MY Hsu… - Basic to Translational …, 2021 - jacc.org
Dysregulated inflammation following myocardial infarction (MI) leads to maladaptive healing
and remodeling. The study characterized and evaluated a selective formyl peptide receptor …