[HTML][HTML] Current insights into atopic march

M Tsuge, M Ikeda, N Matsumoto, T Yorifuji… - Children, 2021 - mdpi.com
The incidence of allergic diseases is increasing, and research on their epidemiology,
pathophysiology, and the prevention of onset is urgently needed. The onset of allergic …

[HTML][HTML] Mast cells in the skin: defenders of integrity or offenders in inflammation?

M Voss, J Kotrba, E Gaffal… - International Journal of …, 2021 - mdpi.com
Mast cells (MCs) are best-known as key effector cells of immediate-type allergic reactions
that may even culminate in life-threatening anaphylactic shock syndromes. However …

[HTML][HTML] Melatonin as an antioxidant and immunomodulator in atopic dermatitis—A new look on an old story: A Review

AK Jaworek, JC Szepietowski, P Hałubiec… - Antioxidants, 2021 - mdpi.com
Atopic dermatitis (AD) is common inflammatory dermatosis, typically with chronic and
recurrent course, which significantly reduces the quality of life. Sleep disturbances are …

[HTML][HTML] Atopic Dermatitis—Beyond the Skin

M Mocanu, D Vâță, AI Alexa, L Trandafir, AI Patrașcu… - Diagnostics, 2021 - mdpi.com
Atopic dermatitis is a chronic inflammatory disease that can arise during the first months of
life or at maturity and have a significant negative impact on the quality of life. The main …

[HTML][HTML] Implication of human bacterial gut microbiota on immune-mediated and autoimmune dermatological diseases and their comorbidities: a narrative review

R Colucci, S Moretti - Dermatology and Therapy, 2021 - Springer
During the last decade, the advent of modern sequencing methods (next generation
techniques, NGS) has helped describe the composition of the human gut microbiome …

[HTML][HTML] Regulation of tissue immune responses by local glucocorticoids at epithelial barriers and their impact on interorgan crosstalk

VM Merk, TS Phan, T Brunner - Frontiers in Immunology, 2021 - frontiersin.org
The anti-inflammatory role of extra-adrenal glucocorticoid (GC) synthesis at epithelial
barriers is of increasing interest with regard to the search for alternatives to synthetic …

The discovery of group 2 innate lymphoid cells has changed the concept of type 2 immune diseases

T Kobayashi, Y Motomura, K Moro - International Immunology, 2021 - academic.oup.com
Group 2 innate lymphoid cells (ILC2s), discovered in 2010, have been recognized as
immune cells with unique functions and their involvement in various diseases has been …

House dust mites–driven allergic rhinitis: could its natural history be modified?

G Ciprandi, MA Tosca - Expert Review of Clinical Immunology, 2021 - Taylor & Francis
Introduction Allergic rhinitis (AR) is the most common IgE-mediated disease. House dust
mites (HDMs)-sensitization is the main cause of AR. HDM-driven AR is characterized by a …

过敏性鼻炎儿童发生支气管哮喘的影响因素分析

叶茂鑫, 刘传合, 沙莉, 谷庆隆, 赵京 - 中国学校卫生, 2021 - cjsh.org.cn
目的探讨过敏性鼻炎患儿发生支气管哮喘的危险因素, 为鼻炎患儿发生哮喘的早期诊断,
治疗和预防提供依据. 方法纳入2019 年11 月至2020 年10 月在首都儿科研究所变态反应科门诊 …

Comorbidities and environmental factors associated with atopic dermatitis in children and adults in dermatology‐venereology in Cotonou, Benin

B Dégboé, F Atadokpèdé, C Nguessie… - Dermatology …, 2021 - Wiley Online Library
Introduction. The objective of this work was to document the comorbidities and
environmental factors associated with atopic dermatitis (AD) in dermatology Venereology in …