Genetic variants of CHEK1, PRIM2 and CDK6 in the mitotic phase‐related pathway are associated with nonsmall cell lung cancer survival
The mitotic phase is a vital step in cell division and may be involved in cancer progression,
but it remains unclear whether genetic variants in mitotic phase‐related pathways genes …
but it remains unclear whether genetic variants in mitotic phase‐related pathways genes …
Role of ERCC5 polymorphisms in non‑small cell lung cancer risk and responsiveness/toxicity to cisplatin‑based chemotherapy in the Chinese population
M Li, R Chen, B Ji, C Fan, G Wang… - Oncology …, 2021 - spandidos-publications.com
Non‑small cell lung cancer (NSCLC) is the leading cause of cancer‑related deaths
worldwide. Cisplatin‑based chemotherapy currently represents the main treatment option for …
worldwide. Cisplatin‑based chemotherapy currently represents the main treatment option for …
[HTML][HTML] Effect of XPD and TP53 gene polymorphisms on the risk of platinum-based chemotherapy induced toxicity in Bangladeshi lung cancer patients
Background: Platinum-based drugs, including cisplatin and carboplatin, are the most active
and extensively used agents for treating lung cancer. Genetic polymorphisms of DNA repair …
and extensively used agents for treating lung cancer. Genetic polymorphisms of DNA repair …
[HTML][HTML] Effect of TOP2A and ERCC1 gene polymorphisms on the efficacy and toxicity of cisplatin and etoposide-based chemotherapy in small cell lung cancer …
M Nicoś, A Rolska-Kopińska, P Krawczyk… - Archives of Medical …, 2021 - ncbi.nlm.nih.gov
Results Patients with C/C genotype in rs13695 of the TOP2A gene had significantly lower
risk of neutropenia during chemotherapy than C/T heterozygous patients (p= 0.02, χ²= 5.51 …
risk of neutropenia during chemotherapy than C/T heterozygous patients (p= 0.02, χ²= 5.51 …
Association of T2285C polymorphism in PARP1 gene coding region with its expression, activity and NSCLC risk along with prognosis
Y Wang, XB Xia, HZ Tang, JR Cai, XK Shi, HX Ji… - …, 2021 - academic.oup.com
Abstract Poly (ADP-ribose) polymerase-1 (PARP1), a DNA repair gene, is the crucial player
in the maintenance of genome integrity. T2285C polymorphism in coding region of PARP1 …
in the maintenance of genome integrity. T2285C polymorphism in coding region of PARP1 …
UTICAJ GENSKIH POLIMORFIZAMA NA TOKSIČNOST PLATINSKE HEMIOTERAPIJE U LEČENJU PACIJENATA SA METASTATSKIM NESITNOĆELIJSKIM …
J Spasic, D Radosavljević… - Medicinski podmladak, 2021 - aseestant.ceon.rs
Sažetak Karcinom pluća je i dalje među najčešćim i najsmrtonosnijim malignim bolestima u
svetu. I pored značajnih pomaka u lečenju uvođenjem ciljane i imunološke terapije …
svetu. I pored značajnih pomaka u lečenju uvođenjem ciljane i imunološke terapije …
The influence of genetic polymorphisms on the toxicity of platinum-based chemotherapy in the treatment of non-small cell lung cancer
J Spasić, D Radosavljević, OL Nagorni - Medicinski podmladak, 2021 - scindeks.ceon.rs
Lung cancer remains one of the most frequent and the deadliest of malignant diseases
throughout the world. Target and immune therapy have revolutionalized the treatment of this …
throughout the world. Target and immune therapy have revolutionalized the treatment of this …