LNCcation: lncRNA localization and function

MC Bridges, AC Daulagala, A Kourtidis - Journal of Cell Biology, 2021 - rupress.org
Subcellular localization of RNAs has gained attention in recent years as a prevalent
phenomenon that influences numerous cellular processes. This is also evident for the large …

Exosomes as powerful engines in cancer: isolation, characterization and detection techniques

MG Saad, H Beyenal, WJ Dong - Biosensors, 2021 - mdpi.com
Exosomes, powerful extracellular nanovesicles released from almost all types of living cells,
are considered the communication engines (messengers) that control and reprogram …

New developments in exosomal lncRNAs in cardiovascular diseases

Z Yuan, W Huang - Frontiers in Cardiovascular Medicine, 2021 - frontiersin.org
Long non-coding RNAs (lncRNAs) are non-coding RNAs with lengths> 200 nt and are
involved in the occurrence and development of cardiovascular diseases (CVDs). Exosomes …

Mediterranean diet enriched in extra-virgin olive oil or nuts modulates circulating exosomal non-coding RNAs

DC Mantilla-Escalante, MC Lopez De las Hazas… - European Journal of …, 2021 - Springer
Purpose Exosomes are extracellular vesicles secreted by cells, which can transport different
molecules, including nucleic acids. Dietary habits may induce gene regulation through the …

Long non‐coding RNA NORAD promotes the prostate cancer cell extracellular vesicle release via microRNA-541-3p-regulated PKM2 to induce bone metastasis of …

C Hu, J Chen, X Qin, P You, J Ma, J Zhang… - Journal of Experimental …, 2021 - Springer
Background Bone metastasis is the leading cause of mortality and reduced quality of life in
patients with metastatic prostate cancer (PCa). Long non-coding RNA activated by DNA …

Muscleblind-like 1 antisense RNA 1 inhibits cell proliferation, invasion, and migration of prostate cancer by sponging miR-181a-5p and regulating PTEN/PI3K/AKT …

X Ding, X Xu, XF He, Y Yuan, C Chen, XY Shen… - …, 2021 - Taylor & Francis
The present study aimed to investigate the role and underlying mechanisms of long non-
coding RNA (lncRNA) muscleblind-like 1 antisense RNA 1 (MBNL1-AS1) in the progression …

Exosomal lncAY927529 enhances prostate cancer cell proliferation and invasion through regulating bone microenvironment

Q Li, J Hu, Y Shi, M Xiao, T Bi, C Wang, L Yan, X Li - Cell Cycle, 2021 - Taylor & Francis
Exosomes mediate the interaction between cancer cells and their microenvironment, and
play a key role in tumor development. Although exosomes can package lncRNAs to mediate …

[HTML][HTML] Extracellular vesicles in prostate cancer: a narrative review

K Hatano, K Fujita - Translational Andrology and Urology, 2021 - ncbi.nlm.nih.gov
Over the past decade, there has been remarkable progress in prostate cancer biomarker
discovery using urine-and blood-based assays. A liquid biopsy is a minimally invasive …

Small extracellular vesicles (sEVs): Discovery, functions, applications, detection methods and various engineered forms

M Negahdaripour, H Owji, S Eskandari… - Expert opinion on …, 2021 - Taylor & Francis
ABSTRACT Introduction Extracellular vesicles (EVs) are cell-created delivery systems of
proteins, lipids, or nucleic acids, and means of extracellular communication. Though sEVs …

Exosomal long non-coding RNA: interaction between cancer cells and non-cancer cells

S Han, Y Qi, Y Luo, X Chen, H Liang - Frontiers in oncology, 2021 - frontiersin.org
Exosomes are small membranous vesicles released by many kinds of cells, and are
indispensable in cell-to-cell communication by delivering functional biological components …