Uromodulin, a protein exclusively produced by the kidney, is the most abundant urinary
protein in physiological conditions. Already described several decades ago, uromodulin has …

Overwhelming lipid peroxidation induces ferroptotic stress and ferroptosis, a nonapoptotic
form of regulated cell death that has been implicated in maladaptive renal repair in mice and …

The correct balance between collagen synthesis and degradation is essential for almost
every aspect of life, from development to healthy aging, reproduction and wound healing …

Background Proteomic profiling may allow identification of plasma proteins that associate
with subsequent changesin kidney function, elucidating biologic processes underlying the …

Variants of transcription factor binding sites (TFBSs) constitute an important part of the
human genome. Current evidence demonstrates close links between nucleotides within …

Protein arginine methyltransferase 5 (PRMT5) symmetrically dimethylates arginine residues
in various proteins affecting diverse cellular processes such as transcriptional regulation …