Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

Abstract Objective Vascular dementia (VaD) is the second most common cause of dementia
and a major health concern worldwide. A comprehensive review on VaD is warranted for …

Stroke is a leading cause of the adult disability epidemic in the United States, with a major
contribution from poststroke cognitive impairment and dementia (PSCID), the rates of which …

Perivascular spaces (PVS) of the brain, often called Virchow-Robin spaces, comprise fluid,
cells and connective tissue, and are externally limited by astrocytic endfeet. PVS are …

We envisage the development of new Brain Health Services to achieve primary and
secondary dementia prevention. These services will complement existing memory clinics by …

The glymphatic system (GS) is a novel defined brain-wide perivascular transit network
between cerebrospinal fluid (CSF) and interstitial solutes that facilitates the clearance of …

Purpose Many daily-life clinical decisions in patients with cerebrovascular disease and
cognitive impairment are complex. Evidence-based information sustaining these decisions …

Background We classified non‐demented European Prevention of Alzheimer's Dementia
(EPAD) participants through the amyloid/tau/neurodegeneration (ATN) scheme and …

Background and Purpose: The causes of recurrent ischemic stroke despite anticoagulation
for atrial fibrillation are uncertain but might include small vessel occlusion. We investigated …

Vascular dementia (VaD) constitutes the second most prevalent cause of dementia in the
world after Alzheimer's disease (AD). VaD regroups heterogeneous neurological conditions …