Selective autophagy is the lysosomal degradation of specific intracellular components
sequestered into autophagosomes, late endosomes, or lysosomes through the activity of …

The liver is a highly dynamic metabolic organ that plays critical roles in plasma protein
synthesis, gluconeogenesis and glycogen storage, cholesterol metabolism and bile acid …

Until recently, radiation effects have been considered to be mainly due to nuclear DNA
damage and their management by repair mechanisms. However, molecular biology studies …

A guiding principle of biology is that biochemical reactions must be organized in space and
time. One way this spatio-temporal organization is achieved is through liquid–liquid phase …

Macroautophagic clearance of cytosolic materials entails the initiation, growth and closure of
autophagosomes. Cargo triggers the assembly of a web of cargo receptors and core …

Physiological reactive oxygen species (ROS) are important regulators of intercellular signal
transduction. Oxidative and antioxidation systems maintain a dynamic balance under …

Protein-rich droplets, such as stress granules, P-bodies, and the nucleolus, perform diverse
and specialized cellular functions. Recent evidence has shown the droplets, which are also …

p62 is a highly conserved, multi-domain, and multi-functional adaptor protein critically
involved in several important cellular processes. Via its pronounced domain architecture …

While starvation‐induced autophagy is thought to randomly degrade cellular components,
under certain circumstances autophagy selectively recognizes, sequesters, and degrades …

Autophagy is a process through which intracellular cargoes are catabolised inside
lysosomes. It involves the formation of autophagosomes initiated by the serine/threonine …