RNA-binding proteins in human genetic disease

F Gebauer, T Schwarzl, J Valcárcel… - Nature Reviews …, 2021 - nature.com
RNA-binding proteins (RBPs) are critical effectors of gene expression, and as such their
malfunction underlies the origin of many diseases. RBPs can recognize hundreds of …

Translational remodeling by RNA‐binding proteins and noncoding RNAs

JJD Ho, JHS Man, JH Schatz… - Wiley Interdisciplinary …, 2021 - Wiley Online Library
Responsible for generating the proteome that controls phenotype, translation is the ultimate
convergence point for myriad upstream signals that influence gene expression. System …

Lactate anions participate in T cell cytokine production and function

J Wen, S Cheng, Y Zhang, R Wang, J Xu, Z Ling… - Science China Life …, 2021 - Springer
After antigen stimulation, T cells preferentially increase aerobic glycolysis to meet the
bioenergetic and biosynthetic demands of T cell activation, proliferation, and effector …

[HTML][HTML] Phosphorylation of mRNA-binding proteins Puf1 and Puf2 by TORC2-activated protein kinase Ypk1 alleviates their repressive effects

HA Galez, FM Roelants, SM Palm, KK Reynaud… - Membranes, 2021 - mdpi.com
Members of the Puf family of RNA-binding proteins typically associate via their Pumilio
homology domain with specific short motifs in the 3'-UTR of an mRNA and thereby influence …

Biolayer interferometry: protein–RNA interactions

SR Martin, A Ramos, L Masino - Protein-Ligand Interactions: Methods and …, 2021 - Springer
RNA-binding proteins often contain multiple RNA-binding domains connected by short
flexible linkers. This domain arrangement allows the protein to bind the RNA with greater …

Identification and expression analysis of chloroplast ribonucleoproteins (cpRNPs) in Arabidopsis and rice

J Wu, H Liu, S Lu, J Hua, B Zou - Genome, 2021 - cdnsciencepub.com
Chloroplast ribonucleoproteins (cpRNPs) are implicated in splicing, editing, and stability
control of chloroplast RNAs as well as in regulating development and stress tolerance. To …

Function and Regulation of Nucleotide Variants in RNA

G Quinones Valdez - 2021 - escholarship.org
RNA molecules harbor the information necessary for the synthesis of proteins and are
essential to a wide variety of cellular processes. Variation of the RNA sequences results in …

[图书][B] Function and Regulation of Nucleotide Variants in RNA

GQ Valdez - 2021 - search.proquest.com
RNA molecules harbor the information necessary for the synthesis of proteins and are
essential to a wide variety of cellular processes. Variation of the RNA sequences results in …