Neural glycomics: The sweet side of nervous system functions

V Sytnyk, I Leshchyns' ka, M Schachner - Cellular and Molecular Life …, 2021 - Springer
The success of investigations on the structure and function of the genome (genomics) has
been paralleled by an equally awesome progress in the analysis of protein structure and …

The IDIP framework for assessing protein function and its application to the prion protein

G Schmitt‐Ulms, M Mehrabian, D Williams… - Biological …, 2021 - Wiley Online Library
The quest to determine the function of a protein can represent a profound challenge.
Although this task is the mandate of countless research groups, a general framework for how …

Spatiotemporal processing of neural cell adhesion molecules 1 and 2 by BACE1 in vivo

WH Kim, H Watanabe, S Lomoio, G Tesco - Journal of Biological Chemistry, 2021 - ASBMB
Neural cell adhesion molecules 1 (NCAM1) and 2 (NCAM2) belong to the cell adhesion
molecules of the immunoglobulin superfamily and have been shown to regulate formation …

PSA depletion induces the differentiation of immature neurons in the piriform cortex of adult mice

S Coviello, B Benedetti, D Jakubecova… - International Journal of …, 2021 - mdpi.com
Immature neurons are maintained in cortical regions of the adult mammalian brain. In
rodents, many of these immature neurons can be identified in the piriform cortex based on …

The loss of polysialic acid impairs the contractile phenotype of peritubular smooth muscle cells in the postnatal testis

NE Hachem, L Humpfle, P Simon, M Kaese… - Cells, 2021 - mdpi.com
In the testis, the germinal epithelium of seminiferous tubules is surrounded by contractile
peritubular cells, which are involved in sperm transport. Interestingly, in postnatal testis …

[PDF][PDF] Modulation of Synaptic AMPA Receptors by Polysialic acid: Potential Future Therapeutics for Neurodegenerative Disorders

L Seay, C Sims, S Bhattacharya, V Suppiramaniam - Methods, 2021 - our.auburn.edu
As the legal use of recreational marijuana changes, women have increasingly begun to use
marijuana to reduce morning sickness while pregnant. The long-term effects that this …

[PDF][PDF] Characterization of the polysialylation machinery in fish

MT Venuto - 2021 - rosdok.uni-rostock.de
Characterization of the polysialylation machinery in fish Page 1 Characterization of the
polysialylation machinery in fish Kumulative Dissertation Zur Erlangung des akademischen …

Impaired Neuronal Plasticity in Alzheimer's Disease: The Role of Calcium, Insulin and Cell Surface Proteins

B Highet - 2021 - researchspace.auckland.ac.nz
Neural cell adhesion molecule (NCAM) undergoes post-translational modification by
addition of polysialic acid (PSA), which disrupts cell adhesive properties and promotes cell …

[HTML][HTML] Altered Brain Connectivity and Behavioural Consequences in Mice with Region-Specific Deletions of the Glycosyltransferase ST8SIA2

M Küçükerden - 2021 - elib.tiho-hannover.de
Altered long-range connectivity is a common finding across neurodevelopmental psychiatric
disorders, but causes and consequences are not well understood. Variations in the gene …

[引用][C] Role of Polysialic Acid in Schizophrenia

C Sato, M Hane, K Kitajima - 2021 - Elsevier