An increasing number of studies have reported that bacterial DNA methylation has important
functions beyond the roles in restriction-modification systems, including the ability of …

Mathematical biology and pharmacology models have a long and rich history in the fields of
medicine and physiology, impacting our understanding of disease mechanisms and the …

Tuberculosis (TB) kills more individuals in the world than any other disease, and a threat
made direr by the coverage of drug-resistant strains of Mycobacterium tuberculosis (Mtb) …

Genome architecture has proven to be critical in determining gene regulation across almost
all domains of life. While many of the key components and mechanisms of eukaryotic …

Mycobacterium tuberculosis can survive within its host for extended periods of time without
any clinical symptoms of disease and reactivate when the immune system is weakened. A …

To promote the development of molecular imprinting technique in the separation and
analysis of protein, novel bovine serum albumin (BSA) surface imprinted nitrogen-doped …

Mycobacteria exploit at least two independent global systems in response to DNA damage:
the LexA/RecA-dependent SOS response and the PafBC-regulated pathway. Intracellular …

Studies of transcription regulation are often focused on binding of transcription factors (TFs)
to a small number of promoters of interest. It is often assumed that TFs are in great excess to …

The role of G-quadruplexes in the cellular physiology of human pathogenesis is an
intriguing area of research. Nonetheless, their functional roles and evolutionary …

The persistence of Mycobacterium tuberculosis (Mtb) is a major problem in managing
tuberculosis (TB). Host-generated nitric oxide (NO) is perceived as one of the signals by Mtb …