Over the last years, respiratory diseases represent a clinical concern, being included among
the leading causes of death in the world due to the lack of effective lung therapies, mainly …

Pulmonary administration route has been extensively exploited for the treatment of local
lung diseases such as asthma, chronic obstructive pulmonary diseases and respiratory …

Globally, there is an urgency to develop effective, low-cost therapeutic interventions for
coronavirus disease 2019 (COVID-19). We previously generated the stable and ultrapotent …

The route of administration of a therapeutic agent has a substantial impact on its success.
Therapeutic antibodies are usually administered systemically, either directly by intravenous …

Oral inhalation is the preferred route for delivery of small molecules to the lungs, because
high tissue levels can be achieved shortly after application. Biologics are mainly …

Leucine is a promising excipient with several applications in the development of inhalable
spray-dried powder of high-and low-dose drugs. The addition of leucine has exhibited …

Therapeutic biologics such as genes, peptides, proteins, virus and cells provide clinical
benefits and are becoming increasingly important tools in respiratory medicine. Pulmonary …

Oral delivery of insulin is of great convenience in treating diabetes but is still subject to the
harsh gastrointestinal tract. Herein, we developed an intelligent oral insulin platform based …

In the present study, the objective was to attain a localized lung delivery of an anti-tubercular
fluoroquinolone, moxifloxacin (MXF), targeting the alveolar macrophages through a non …

SARS-CoV-2 remains a global threat to human health particularly as escape mutants
emerge. There is an unmet need for effective treatments against COVID-19 for which …