Intellectual disability (ID) and autism spectrum disorder (ASD) are the most common
neurodevelopmental disorders and are characterized by substantial impairment in …

Promoting residential cells, particularly endogenous neural stem and progenitor cells
(NSPCs), for tissue regeneration represents a potential strategy for the treatment of spinal …

How homeodomain proteins gain sufficient specificity to control different cell fates has been
a long-standing problem in developmental biology. The conserved Gsx homeodomain …

Innate behavioral biases such as human handedness are a ubiquitous form of inter-
individual variation that are not strictly hardwired into the genome and are influenced by …

Direct reprogramming technology allows several specific types of cells, including
specialized neurons, to be obtained from readily available autologous somatic cells. It …

The transcription factor SOX2 is important for brain development and for neural stem cells
(NSC) maintenance. Sox2-deleted (Sox2-del) NSC from neonatal mouse brain are lost after …

Abstract Specification of the progenitors' regional identity is a pivotal step during
development of the cerebral cortex and basal ganglia. The molecular mechanisms …

Progenitors in the dorsal lateral ganglionic eminence (dLGE) are known to give rise to
olfactory bulb (OB) interneurons and intercalated cells (ITCs) of the amygdala. The dLGE …

Технология прямого репрограммирования позволяет получать различные
специфические типы клеток, включая специализированные нейроны, из легко …

Restless legs syndrome (RLS) is a common neurological disorder with a substantial genetic
contribution. A genome-wide association study (GWAS) identified MEIS1 as the strongest …