[HTML][HTML] Targeting inflammation in atherosclerosis—from experimental insights to the clinic

O Soehnlein, P Libby - Nature reviews Drug discovery, 2021 - nature.com
Atherosclerosis, a dominant and growing cause of death and disability worldwide, involves
inflammation from its inception to the emergence of complications. Targeting inflammatory …

The changing landscape of atherosclerosis

P Libby - Nature, 2021 - nature.com
Emerging evidence has spurred a considerable evolution of concepts relating to
atherosclerosis, and has called into question many previous notions. Here I review this …

Global epidemiology of valvular heart disease

S Coffey, R Roberts-Thomson, A Brown… - Nature Reviews …, 2021 - nature.com
Valvular heart disease (VHD) is a major contributor to loss of physical function, quality of life
and longevity. The epidemiology of VHD varies substantially around the world, with a …

Lower extremity peripheral artery disease: contemporary epidemiology, management gaps, and future directions: a scientific statement from the American Heart …

MH Criqui, K Matsushita, V Aboyans, CN Hess… - Circulation, 2021 - Am Heart Assoc
Lower extremity peripheral artery disease (PAD) affects> 230 million adults worldwide and is
associated with increased risk of various adverse clinical outcomes (other cardiovascular …

[HTML][HTML] Pollution and the heart

S Rajagopalan, PJ Landrigan - New England Journal of Medicine, 2021 - Mass Medical Soc
Pollution and the Heart Environmental pollution is a cardiovascular risk factor. The Global
Burden of Disease study estimated that pollution caused 9 million deaths in 2019, of which …

[HTML][HTML] Impact of Mediterranean diet on chronic non-communicable diseases and longevity

LJ Dominguez, G Di Bella, N Veronese, M Barbagallo - Nutrients, 2021 - mdpi.com
The average life expectancy of the world population has increased remarkably in the past
150 years and it is still increasing. A long life is a dream of humans since the beginning of …

Fixed-dose combination therapies with and without aspirin for primary prevention of cardiovascular disease: an individual participant data meta-analysis

P Joseph, G Roshandel, P Gao, P Pais, E Lonn… - The Lancet, 2021 - thelancet.com
Background In randomised controlled trials, fixed-dose combination treatments (or polypills)
have been shown to reduce a composite of cardiovascular disease outcomes in primary …

The heart failure association atlas: heart failure epidemiology and management statistics 2019

PM Seferović, P Vardas, EA Jankowska… - European journal of …, 2021 - Wiley Online Library
Aims The Heart Failure Association (HFA) of the European Society of Cardiology (ESC)
developed the HFA Atlas to provide a contemporary description of heart failure (HF) …

Efficacy of a digital therapeutics system in the management of essential hypertension: the HERB-DH1 pivotal trial

K Kario, A Nomura, N Harada, A Okura… - European heart …, 2021 - academic.oup.com
Aims Digital therapeutics is a new approach to facilitate the non-pharmacological treatment
of hypertension using software programmes such as smartphone applications and/or device …

Lower extremity peripheral artery disease without chronic limb-threatening ischemia: a review

TS Polonsky, MM McDermott - Jama, 2021 - jamanetwork.com
Importance Lower extremity peripheral artery disease (PAD) affects approximately 8.5
million people in the US and approximately 230 million worldwide. Observations Peripheral …