Burden of pneumococcal disease among adults in Southern Europe (Spain, Portugal, Italy, and Greece): A systematic review and meta-analysis

A Navarro-Torné, EA Montuori… - Human Vaccines & …, 2021 - Taylor & Francis
The aim was to summarize pneumococcal disease burden data among adults in Southern
Europe and the potential impact of vaccines on epidemiology. Of 4779 identified studies …

Lymphopenia is associated with poor outcomes of patients with community-acquired pneumonia and sepsis

C Cilloniz, HJ Peroni, A Gabarrús… - Open Forum …, 2021 - academic.oup.com
Background Lymphopenia is a marker of poor prognosis in patients with community-
acquired pneumonia (CAP), yet its impact on outcomes in patients with CAP and sepsis …

[HTML][HTML] Evaluation of a novel urinary antigen test kit for diagnosing Legionella pneumonia

A Ito, Y Yamamoto, Y Ishii, A Okazaki, Y Ishiura… - International Journal of …, 2021 - Elsevier
Objectives The aim of this study was to evaluate the diagnostic utility of a novel test kit that
could theoretically detect all serogroups of Legionella pneumophila for diagnosing …

Validation of a prediction score for drug-resistant microorganisms in community-acquired pneumonia

A Ceccato, R Mendez, S Ewig… - Annals of the …, 2021 - atsjournals.org
Rationale: Recommended initial empiric antimicrobial treatment covers the most common
bacterial pathogens; however, community-acquired pneumonia (CAP) may be caused by …

Methicillin-susceptible staphylococcus aureus in community-acquired pneumonia: Risk factors and outcomes

C Cilloniz, C Dominedò, A Gabarrus, C Garcia-Vidal… - Journal of Infection, 2021 - Elsevier
Objectives We aimed to describe the prevalence, risk factors and outcomes of Methicillin-
susceptible S. aureus (MSSA) community-acquired pneumonia (CAP) and compare them …

[HTML][HTML] Time trend of the sensitivity of the pneumococcal urinary antigen test for diagnosing pneumococcal community-acquired pneumonia: an analysis of 15-year …

A Ito, T Ishida, H Tachibana, Y Nakanishi… - Infectious Diseases and …, 2021 - Springer
Introduction Whether the sensitivity of the BinaxNOW Streptococcus pneumoniae urinary
antigen test kit (BinaxNOW), adjusted by some variables including vital signs, laboratory …

Heightened Local Th17 Cell Inflammation Is Associated with Severe Community‐Acquired Pneumonia in Children under the Age of 1 Year

M Liu, B Lu, H Fan, X Guo, S Du, D Yang… - Mediators of …, 2021 - Wiley Online Library
Severe community‐acquired pneumonia (sCAP) early in life is a leading cause of morbidity,
mortality, and irreversible sequelae. Herein, we report the clinical, etiological, and …

[HTML][HTML] Lefamulin in patients with community-acquired bacterial pneumonia caused by atypical respiratory pathogens: pooled results from two phase 3 trials

S Paukner, D Mariano, AF Das, GJ Moran, C Sandrock… - Antibiotics, 2021 - mdpi.com
Lefamulin was the first systemic pleuromutilin antibiotic approved for intravenous and oral
use in adults with community-acquired bacterial pneumonia based on two phase 3 trials …

Community-acquired pneumonia: Trends in and research on drug resistance and advances in new antibiotics

L Shen, L Wang, C Liu, S Shi, T Takahashi… - Bioscience …, 2021 - jstage.jst.go.jp
Community-acquired pneumonia (CAP) refers to infectious inflammation of the lung
parenchyma developing outside of a hospital. CAP has quite a high mortality and morbidity …

[HTML][HTML] Diagnosis of Streptococcus pneumoniae infection using circulating antibody secreting cells

S Kyu, RP Ramonell, M Kuruvilla, CS Kraft, YF Wang… - PLoS …, 2021 - journals.plos.org
Background Streptococcus pneumoniae infections cause morbidity and mortality worldwide.
A rapid, simple diagnostic method could reduce the time needed to introduce definitive …