Vaccination as a preventative measure contributing to immune fitness
B Laupèze, G Del Giudice, MT Doherty, R Van der Most - npj Vaccines, 2021 - nature.com
The primary goal of vaccination is the prevention of pathogen-specific infection. The indirect
consequences may include maintenance of homeostasis through prevention of infection …
consequences may include maintenance of homeostasis through prevention of infection …
Is early life adversity a trigger towards inflammageing?
MP Merz, JD Turner - Experimental Gerontology, 2021 - Elsevier
There are many 'faces' of early life adversity (ELA), such as childhood trauma,
institutionalisation, abuse or exposure to environmental toxins. These have been implicated …
institutionalisation, abuse or exposure to environmental toxins. These have been implicated …
Estimage: a webserver hub for the computation of methylation age
Methylage is an epigenetic marker of biological age that exploits the correlation between the
methylation state of specific CG dinucleotides (CpGs) and chronological age (in years) …
methylation state of specific CG dinucleotides (CpGs) and chronological age (in years) …
Chromatin alterations in the aging lung change progenitor cell activity
SP Rowbotham, P Pessina, CG de Alba Rivas, J Li… - bioRxiv, 2021 - biorxiv.org
The lung contains multiple progenitor cell types that respond to damage, but how their
responses are choreographed and why they decline with age is poorly understood. We …
responses are choreographed and why they decline with age is poorly understood. We …
Differences in Cortical Thickness Between Cognitively Impaired Persons With and Without Apathy May Reflect Discrete Mechanisms of Neuropathophysiology
NK Chan - 2021 - search.proquest.com
Apathy increases the risk of dementia and is associated with worse outcomes. Deficits in
frontostriatal circuits and frontotemporal association areas are associated with apathy in …
frontostriatal circuits and frontotemporal association areas are associated with apathy in …