Evidence of an antidepressant-like effect of xylopic acid mediated by serotonergic mechanisms

RP Biney, CK Benneh, DW Adongo, EO Ameyaw… - …, 2021 - Springer
Background Depression causes significant debilitating symptoms and economic burden.
Current management is challenged by slow onset of action and modest efficacies of …

Potential antidepressant-like effect of piperazine derivative LQFM212 in mice: Role of monoaminergic pathway and brain-derived neurotrophic factor

LK da Silva Moreira, AF de Brito, DM da Silva… - Behavioural Brain …, 2021 - Elsevier
Major depression disorder (MDD) is one of the most widespread and debilitating psychiatric
diseases and may be associated with other mental disorders such as anxiety. Despite …

Antidepressant-like effect of Albizia zygia root extract in murine models

VWA Kumbol, WKM Abotsi, RP Biney - Journal of Basic and Clinical …, 2021 - degruyter.com
Abstract Background Albizia zygia (DC.) JF Macbr.(Leguminosae) has been used to treat
mental disorders in traditional African medicine. Nonetheless, there is limited scientific …

Serotonin Synthesis Inhibition by Para-Chlorophenylalanine Impairs Defensive Reactions of Aversive Learning and Long-term Sensitization in Terrestrial Snails

AW Chihab, VV Andrianov, TK Bogodvid, IB Deryabina… - BioNanoScience, 2021 - Springer
In this paper, we present a study of the effects of reducing serotonin levels by para-
chlorophenylalanine (PCPA), an inhibitor of tryptophan hydroxylase, the limiting enzyme in …

[PDF][PDF] Research Article Antidepressant-Like Effect of the Leaves of Pseudospondias microcarpa in Mice: Evidence for the Involvement of the Serotoninergic System …

DW Adongo, KKE Kukuia, PK Mante, EO Ameyaw… - academia.edu
Depression continues to be a major global health problem. Although antidepressants are
used for its treatment, efficacy is often inconsistent. Thus, the search for alternative …