Potential alternatives to current cholinesterase inhibitors: an in silico drug repurposing approach

D Kundu, VK Dubey - Drug Development and Industrial Pharmacy, 2021 - Taylor & Francis
Acetylcholinesterase/Butyrylcholinesterase inhibitors are considered an effective method for
treating Alzheimer's disease (AD). In this current work, we have computationally analyzed 11 …

Antimalarial activity of curcumin and kaempferol using structure-based drug design method‎

MY Alkandahri, R Patala, A Berbudi… - Journal of Advanced …, 2021 - japer.in
Malaria is a major global health problem caused by plasmodium parasites. The alarming
spread of drug resistance and its limited availability underscores the importance of …

[HTML][HTML] Glucosylation of (±)-menthol by uridine-diphosphate-sugar dependent glucosyltransferases from plants

E Kurze, V Ruß, N Syam, I Effenberger, R Jonczyk… - Molecules, 2021 - mdpi.com
Menthol is a cyclic monoterpene alcohol of the essential oils of plants of the genus Mentha,
which is in demand by various industries due to its diverse sensorial and physiological …

Mammalian DNA methyltransferase DNMT1: structure and function analysis and development of novel inhibitors using in silico methods

M Rijako - 2021 - zir.nsk.hr
Background: DNA methylation is considered a basic and longest-lasting mechanism of
human genome organization. It is established during embryogenesis and lasts for the …