Neurologic manifestations of the antiphospholipid syndrome—an update

M Leal Rato, M Bandeira, VC Romão… - Current Neurology and …, 2021 - Springer
Abstract Purpose of Review In recent years, the spectrum of neurological manifestations of
antiphospholipid syndrome (APS) has been growing. We provide a critical review of the …

A systematic review of the association between anti-β-2 glycoprotein I antibodies and APS manifestations

D Jiang, W Lim, M Crowther, D Garcia - Blood Advances, 2021 - ashpublications.org
Anti-β-2 glycoprotein I antibodies (anti-B2GPI) are often cited as the major pathogenically
relevant antibody in antiphospholipid syndrome (APS), but it is unclear if there is clinical …

Presence of extra-criteria antiphospholipid antibodies is an independent risk factor for ischemic stroke

L Naranjo, F Ostos, FJ Gil-Etayo… - Frontiers in …, 2021 - frontiersin.org
Background: Ischemic stroke is the most common and severe arterial thrombotic event in
Antiphospholipid syndrome (APS). APS is an autoimmune disease characterized by the …

Anti‐phospholipid antibodies and reproductive failures

A Beltagy, L Trespidi, M Gerosa… - American Journal of …, 2021 - Wiley Online Library
Anti‐phospholipid syndrome (APS) recapitulates the link between autoimmunity and
pregnancy failure: Acquired anti‐phospholipid antibodies (aPL) play a pathogenic role in …

Understanding the pathophysiology of thrombotic APS through animal models

AA Gandhi, SK Estes, CE Rysenga… - International journal of …, 2021 - mdpi.com
Antiphospholipid syndrome (APS) is a leading acquired cause of thrombotic events, with a
notable tendency to promote thrombosis in vascular beds of all sizes, including both arterial …

B cells in primary antiphospholipid syndrome: Review and remaining challenges

Y Dieudonné, A Guffroy, V Poindron, PS Sprauel… - Autoimmunity …, 2021 - Elsevier
It is now widely accepted that antiphospholipid antibodies (aPL) have direct pathogenic
effects and that B cells, notably through aPL production, play a key role in the development …

Antiphospholipid antibodies in critically ill COVID-19 patients with thromboembolism: cause of disease or epiphenomenon?

V Pavoni, L Gianesello, A Horton - Journal of Thrombosis and …, 2021 - Springer
Abstract Coronavirus 2019 disease (COVID-19) is associated with coagulation dysfunction
that predisposes patients to an increased risk for both arterial (ATE) and venous …

Impaired fibrinolysis in the antiphospholipid syndrome

A Antovic, M Bruzelius - Seminars in Thrombosis and …, 2021 - thieme-connect.com
The pathogenesis of the antiphospholipid syndrome (APS) is complex and involves the
persistent presence of antiphospholipid antibodies (aPL) in the bloodstream causing a …

Longitudinal analysis of anti-cardiolipin and anti-β2-glycoprotein-I antibodies in recent-onset systemic lupus erythematosus: a prospective study in Swedish patients

M Frodlund, T Walhelm, C Dahle, C Sjöwall - Frontiers in Medicine, 2021 - frontiersin.org
Background: Anti-phospholipid syndrome (APS) and systemic lupus erythematous (SLE) are
autoimmune disorders that often co-occur. Anti-phospholipid antibodies (aPL) are typical of …

Role of autoantibodies in infertility, miscarriage, and assisted reproductive technology outcomes

HH Shen, ZZ Lai, HL Yang, JW Shi… - Reproductive and …, 2021 - mednexus.org
Although considerable advances have been made in the field of assisted reproductive
technology (ART), millions of couples still suffer from infertility and miscarriage. In a large …