Astrocyte and glutamate involvement in the pathogenesis of epilepsy in Alzheimer's disease
Alzheimer's disease (AD) can increase the risk of epilepsy by up to 10‐fold compared to
healthy age‐matched controls. However, the pathological mechanisms that underlie this …
healthy age‐matched controls. However, the pathological mechanisms that underlie this …
Pretreatment with a glutamine synthetase inhibitor MSO delays the onset of initial seizures induced by pilocarpine in juvenile rats
MJ Pawlik, M Obara-Michlewska, MP Popek… - Brain research, 2021 - Elsevier
The contribution of glutamatergic transmission to generation of initial convulsive seizures
(CS) is debated. We tested whether pretreatment with a glutamine synthetase (GS) inhibitor …
(CS) is debated. We tested whether pretreatment with a glutamine synthetase (GS) inhibitor …
[HTML][HTML] Inhibition of glutamate release, but not of glutamine recycling to glutamate, is involved in delaying the onset of initial lithium-pilocarpine-induced seizures in …
MJ Pawlik, BI Aldana, LF Belfiori-Carrasco… - International Journal of …, 2021 - mdpi.com
Initial seizures observed in young rats during the 60 min after administration of pilocarpine
(Pilo) were delayed and attenuated by pretreatment with a non-convulsive dose of …
(Pilo) were delayed and attenuated by pretreatment with a non-convulsive dose of …
Mechanistic Insight into the Attenuation of Initial Pilocarpine-Induced Seizures in Young Rats by a Non-Convulsive MSO Dose
MJ Pawlik, BI Aldana, LF Belfiori-Carrasco… - 2021 - preprints.org
Pretreatment with non-convulsive dose of methionine sulfoximine (MSO) attenuated lithi-um-
pilocarpine-induced (Li-Pilo) seizures in young rats [1]. We hypothesized that the effect of …
pilocarpine-induced (Li-Pilo) seizures in young rats [1]. We hypothesized that the effect of …
[HTML][HTML] Characterization of an unusual murine glial cell population in dorsal root ganglia
B Huang - 2021 - elib.tiho-hannover.de
Dorsal root ganglia (DRG) represent accumulations of neurons located near the neural
foramina at the dorsal root of each spinal nerve. They contain pseudounipolar neurons with …
foramina at the dorsal root of each spinal nerve. They contain pseudounipolar neurons with …