For many retinal diseases, including age-related macular degeneration (AMD), glaucoma,
and diabetic retinopathy (DR), the exact pathogenesis is still unclear. Moreover, the currently …

Glaucoma is a disease associated with the loss of retinal ganglion cells (RGCs), and
remains one of the primary causes of blindness worldwide. Major research efforts are …

Pachychoroid spectrum diseases have been described as a new clinical entity within the
spectrum of macular disorders.“Pachychoroid” is defined as choroidal thickening associated …

Background: To compare two prolonged animal models of glaucoma over 24 weeks of
follow-up. A novel pre-trabecular model of chronic glaucoma was achieved by injection of …

The aim of this study was to evaluate repeatability, reproducibility, and agreement of three
commonly used tonometers in animal research (TonoLab, TonoVet, and TonoPEN AVIA) in …

Progressive degeneration of neuroretinal tissue with maintained elevated intraocular
pressure (IOP) to simulate chronic glaucoma was produced by intracameral injections of …

Purpose: To evaluate differences by sex in the neuroretina of rats with chronic glaucoma
over 24 weeks of follow-up, and to assess by sex the influence on neurodegeneration of …

Despite being one of the most studied eye diseases, clinical translation of glaucoma
research is hampered, at least in part, by the lack of validated preclinical models and …

Background Acute angle-closure glaucoma (AACG) is an ophthalmic emergency that occurs
over the course of hours or days and may cause irreversible blindness if not treated …

Normal retina and its cell layers are essential for processing visual stimuli, and loss of its
integrity has been documented in many disease processes. The numbers and the axonal …