Pan-cancer analysis of NLRP3 inflammasome with potential implications in prognosis and immunotherapy in human cancer

M Ju, J Bi, Q Wei, L Jiang, Q Guan… - Briefings in …, 2021 - academic.oup.com
NLRP3 inflammasome was introduced as a double-edged sword in tumorigenesis and
influenced immunotherapy response by modulating host immunity. However, a systematic …

Inflammasomes and the maintenance of hematopoietic homeostasis: new perspectives and opportunities

L Yang, M Hu, Y Lu, S Han, J Wang - Molecules, 2021 - mdpi.com
Hematopoietic stem cells (HSCs) regularly produce various blood cells throughout life via
their self-renewal, proliferation, and differentiation abilities. Most HSCs remain quiescent in …

The NLRP3 inflammasome and its role in the pathogenicity of leukemia

L Urwanisch, M Luciano, J Horejs-Hoeck - International journal of …, 2021 - mdpi.com
Chronic inflammation contributes to the development and progression of various tumors.
Especially where the inflammation is mediated by cells of the innate immune system, the …

Inflammasome signaling: A novel paradigm of hub platform in innate immunity for cancer immunology and immunotherapy

Y Li, J Lv, W Shi, J Feng, M Liu, S Gan, H Wu… - Frontiers in …, 2021 - frontiersin.org
Inflammasomes are fundamental innate immune mechanisms that promote inflammation
and induce an inflammatory form of programmed cell death, pyroptosis. Pyroptotic …

Malignancy risk of immunoglobin G4-related disease: evidence from a large cohort multicenter retrospective study

Y Liu, J Fu, X Ning, H Li, X Ma, K Wang, W Bian… - Rheumatology and …, 2021 - Springer
Introduction The aim of this work was to evaluate the prevalence of malignancies in a
multicenter cohort of Chinese patients with immunoglobulin G4-related disease (IgG4-RD) …

Malignancy Risk of Immunoglobin G4-related Disease: Evidence From a Large Cohort Multicenter Study

Y Liu, J Fu, X Ning, H Li, X Ma, K Wang, W Bian… - 2021 - researchsquare.com
Objective: To evaluate the prevalence of malignancies in a multicenter cohort of Chinese
patients with immunoglobulin G4-related disease (IgG4-RD) and to identify the related risk …