Exosome‐mediated pyroptosis of miR‐93‐TXNIP‐NLRP3 leads to functional difference between M1 and M2 macrophages in sepsis‐induced acute kidney injury

CX Juan, Y Mao, Q Cao, Y Chen… - Journal of cellular …, 2021 - Wiley Online Library
Sepsis is a systemic inflammatory response syndrome caused by infection, resulting in
organ dysfunction. Sepsis‐induced acute kidney injury (AKI) is one of the most common …

Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin

JS Wang, T Kamath, CM Mazur… - Nature …, 2021 - nature.com
Some osteoblasts embed within bone matrix, change shape, and become dendrite-bearing
osteocytes. The circuitry that drives dendrite formation during “osteocytogenesis” is poorly …

Evaluation of the MGISEQ-2000 sequencing platform for Illumina target capture sequencing libraries

J Lang, R Zhu, X Sun, S Zhu, T Li, X Shi, Y Sun… - Frontiers in …, 2021 - frontiersin.org
Illumina is the leading sequencing platform in the next-generation sequencing (NGS) market
globally. In recent years, MGI Tech has presented a series of new sequencers, including …

Differential RNA packaging into small extracellular vesicles by neurons and astrocytes

X Luo, R Jean-Toussaint, A Sacan, SK Ajit - Cell Communication and …, 2021 - Springer
Background Small extracellular vesicles (sEVs) mediate intercellular communication by
transferring RNA, proteins, and lipids to recipient cells. These cargo molecules are …

Developmental validation of the MGIEasy Signature Identification Library Prep Kit, an all-in-one multiplex system for forensic applications

R Li, X Shen, H Chen, D Peng, R Wu, H Sun - International Journal of …, 2021 - Springer
Analyzing genetic markers in nuclear and mitochondrial genomes is helpful in various
forensic applications, such as individual identifications and kinship analyses. However, most …

Distinct miRNA signatures and networks discern fetal from adult erythroid differentiation and primary from immortalized erythroid cells

PL Papasavva, NY Papaioannou, P Patsali… - International journal of …, 2021 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs crucial for post-transcriptional and
translational regulation of cellular and developmental pathways. The study of miRNAs in …

A SNP of HD-ZIP I transcription factor leads to distortion of trichome morphology in cucumber (Cucumis sativus L.)

L Zhang, D Lv, J Pan, K Zhang, H Wen, Y Chen, H Du… - BMC Plant …, 2021 - Springer
Background Trichomes are excellent model systems for the analysis of cell differentiation
and play essential roles in plant protection. From cucumber inbred line 'WD1', we identified …

[HTML][HTML] RNA-seq identifies circulating miRNAs as potential biomarkers for plaque rupture in patients with ST-segment elevation myocardial infarction

J Li, Y Tan, Z Sheng, P Zhou, C Liu, H Zhao, L Song… - Genomics, 2021 - Elsevier
Background Plaque rupture (PR) and plaque erosion (PE) are the two major pathological
phenotypes in acute coronary syndrome. Since microRNAs have been found to be involved …

[HTML][HTML] Efficient and stable metabarcoding sequencing data using a DNBSEQ-G400 sequencer validated by comprehensive community analyses

X Sun, YH Hu, J Wang, C Fang, J Li, M Han, X Wei… - Gigabyte, 2021 - ncbi.nlm.nih.gov
Metabarcoding is a widely used method for fast characterization of microbial communities in
complex environmental samples. However, the selction of sequencing platform can have a …

A novel forensic panel of 186-plex SNPs and 123-plex STR loci based on massively parallel sequencing

X Miao, Y Shen, X Gong, H Yu, B Li, L Chang… - International Journal of …, 2021 - Springer
Abstract The MiSeq® FGX Forensic system and the HID-Ion AmpliSeq Panel were
previously developed for massively parallel sequencing (MPS) for forensic casework …