[HTML][HTML] Lyophyllin, a mushroom protein from the peptidase M35 superfamily is an RNA N-glycosidase

JQ Lu, WW Shi, MJ Xiao, YS Tang, YT Zheng… - International Journal of …, 2021 - mdpi.com
Ribosome-inactivating proteins (RIPs) hydrolyze the N-glycosidic bond and depurinate a
specific adenine residue (A-4324 in rat 28S ribosomal RNA, rRNA) in the conserved α …

AP sites in various mRNA positions cross-link to the protein uS3 in the translating mammalian ribosome

AS Ochkasova, MI Meschaninova… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Abasic (AP) sites in mRNAs are lesions whose accumulation in cells is linked to various
neurodegenerative diseases arising from the appearance of truncated peptides due to the …

[HTML][HTML] Two alternative conformations of mRNA in the human ribosome during elongation and termination of translation as revealed by EPR spectroscopy

KN Bulygin, IO Timofeev, AA Malygin… - Computational and …, 2021 - Elsevier
The conformation of mRNA in the region of the human 80S ribosome decoding site was
monitored using 11-mer mRNA analogues that bore nitroxide spin labels attached to the …