Intrinsic and extrinsic pathways of apoptosis: Role in cancer development and prognosis

D Kashyap, VK Garg, N Goel - Advances in protein chemistry and structural …, 2021 - Elsevier
Apoptosis, also named programmed cell death, is a fundament process required for
morphogenetic homeostasis during early development and in pathophysiological …

[HTML][HTML] Ursolic and oleanolic acids: Plant metabolites with neuroprotective potential

E Gudoityte, O Arandarcikaite, I Mazeikiene… - International Journal of …, 2021 - mdpi.com
Ursolic and oleanolic acids are secondary plant metabolites that are known to be involved in
the plant defence system against water loss and pathogens. Nowadays these triterpenoids …

Rosemary (Rosmarinus officinalis L.): extraction techniques, analytical methods and health-promoting biological effects

S Lešnik, V Furlan, U Bren - Phytochemistry Reviews, 2021 - Springer
Rosemary (Rosmarinus officinalis L.) of the Lamiaceae family represents an evergreen
medicinal plant with various health-promoting pharmacological effects. This paper provides …

[HTML][HTML] Anti-inflammatory and anticancer properties of birch bark-derived betulin: Recent developments

HS Tuli, K Sak, DS Gupta, G Kaur, D Aggarwal… - Plants, 2021 - mdpi.com
Birch tree bark-derived betulin has attracted scientific interest already for several centuries,
being one of the first natural products identified from plants. However, the cellular events …

[HTML][HTML] Antitumor effects of ursolic acid through mediating the inhibition of STAT3/PD-L1 signaling in non-small cell lung cancer cells

DY Kang, N Sp, JM Lee, KJ Jang - Biomedicines, 2021 - mdpi.com
Targeted therapy based on natural compounds is one of the best approaches against non-
small cell lung cancer. Ursolic acid (UA), a pentacyclic triterpenoid derived from medicinal …

[HTML][HTML] Recent advancement in chitosan-based nanoparticles for improved oral bioavailability and bioactivity of phytochemicals: Challenges and perspectives

SS Imam, S Alshehri, MM Ghoneim, A Zafar… - Polymers, 2021 - mdpi.com
The excellent therapeutic potential of a variety of phytochemicals in different diseases has
been proven by extensive studies throughout history. However, most phytochemicals are …

Chitosan modified poly (lactic acid) nanoparticles increased the ursolic acid oral bioavailability

E Antonio, ORA Junior, RGDJV Marcano… - International Journal of …, 2021 - Elsevier
Ursolic acid (UA) is a naturally occurring triterpene that has been investigated for its
antitumor activity. However, its lipophilic character hinders its oral bioavailability, and …

Quercetin as a novel therapeutic approach for lymphoma

SR Soofiyani, K Hosseini… - Oxidative Medicine …, 2021 - Wiley Online Library
Lymphoma is a name for malignant diseases of the lymphatic system including Hodgkin's
lymphoma and non‐Hodgkin's lymphoma. Although several approaches are used for the …

[HTML][HTML] Therapeutic potential of ursolic acid in cancer and diabetic neuropathy diseases

M Alam, S Ali, S Ahmed, AM Elasbali, M Adnan… - International journal of …, 2021 - mdpi.com
Ursolic acid (UA) is a pentacyclic triterpenoid frequently found in medicinal herbs and plants,
having numerous pharmacological effects. UA and its analogs treat multiple diseases …

Dietary Ursolic Acid Prevents Alcohol-Induced Liver Injury via Gut–Liver Axis Homeostasis Modulation: The Key Role of Microbiome Manipulation

X Yan, X Ren, X Liu, Y Wang, J Ma… - Journal of Agricultural …, 2021 - ACS Publications
Ursolic acid (UA), a natural triterpenoid widely distributed within fruits and edible plants, has
been proven to relieve alcoholic liver disease (ALD). However, the mechanisms involved …