A focus on secondary progressive multiple sclerosis (SPMS): challenges in diagnosis and definition
H Inojosa, U Proschmann, K Akgün, T Ziemssen - Journal of neurology, 2021 - Springer
Secondary progressive multiple sclerosis (SPMS) is the second most common form of
multiple sclerosis (MS). One in two relapse remitting multiple sclerosis (RRMS) patients will …
multiple sclerosis (MS). One in two relapse remitting multiple sclerosis (RRMS) patients will …
Diagnosis of progressive multiple sclerosis from the imaging perspective: a review
M Filippi, P Preziosa, F Barkhof, DT Chard… - JAMA …, 2021 - jamanetwork.com
Importance Although magnetic resonance imaging (MRI) is useful for monitoring disease
dissemination in space and over time and excluding multiple sclerosis (MS) mimics, there …
dissemination in space and over time and excluding multiple sclerosis (MS) mimics, there …
Effect of disease-modifying therapy on disability in relapsing-remitting multiple sclerosis over 15 years
Objective To test the hypothesis that immunotherapy prevents long-term disability in
relapsing-remitting multiple sclerosis (MS), we modeled disability outcomes in 14,717 …
relapsing-remitting multiple sclerosis (MS), we modeled disability outcomes in 14,717 …
Natalizumab, fingolimod, and dimethyl fumarate use and pregnancy-related relapse and disability in women with multiple sclerosis
Objective To investigate pregnancy-related disease activity in a contemporary multiple
sclerosis (MS) cohort. Methods Using data from the MSBase Registry, we included …
sclerosis (MS) cohort. Methods Using data from the MSBase Registry, we included …
NfL predicts relapse-free progression in a longitudinal multiple sclerosis cohort study
T Uphaus, F Steffen, M Muthuraman, N Ripfel… - …, 2021 - thelancet.com
Background Easily accessible biomarkers enabling the identification of those patients with
multiple sclerosis (MS) who will accumulate irreversible disability in the long term are …
multiple sclerosis (MS) who will accumulate irreversible disability in the long term are …
Increased serum neurofilament light and thin ganglion cell–inner plexiform layer are additive risk factors for disease activity in early multiple sclerosis
Objective To investigate the association of combined serum neurofilament light chain (sNfL)
and retinal optical coherence tomography (OCT) measurements with future disease activity …
and retinal optical coherence tomography (OCT) measurements with future disease activity …
Longitudinal machine learning modeling of MS patient trajectories improves predictions of disability progression
Abstract Background and Objectives Research in Multiple Sclerosis (MS) has recently
focused on extracting knowledge from real-world clinical data sources. This type of data is …
focused on extracting knowledge from real-world clinical data sources. This type of data is …
Deciphering multiple sclerosis progression
V Meca-Lallana, L Berenguer-Ruiz… - Frontiers in …, 2021 - frontiersin.org
Multiple sclerosis (MS) is primarily an inflammatory and degenerative disease of the central
nervous system, triggered by unknown environmental factors in patients with predisposing …
nervous system, triggered by unknown environmental factors in patients with predisposing …
Real‐world experience of ocrelizumab in multiple sclerosis in a Spanish population
E Fernandez‐Diaz, JA Perez‐Vicente… - Annals of Clinical …, 2021 - Wiley Online Library
Objective Pivotal trial have shown that patients with multiple sclerosis (MS) receiving
ocrelizumab had better outcomes. However, data on ocrelizumab in clinical practice are …
ocrelizumab had better outcomes. However, data on ocrelizumab in clinical practice are …
Evolution of brain volume loss rates in early stages of multiple sclerosis
Objective To describe the dynamics of brain volume loss (BVL) at different stages of
relapsing-remitting multiple sclerosis (RRMS), to describe the association between BVL and …
relapsing-remitting multiple sclerosis (RRMS), to describe the association between BVL and …