Does a strict glycemic control during acute coronary syndrome play a cardioprotective effect? Pathophysiology and clinical evidence

A Caturano, R Galiero, PC Pafundi, A Cesaro… - Diabetes research and …, 2021 - Elsevier
A hyperglycemic state, also in non-diabetic subjects, may be associated with acute coronary
syndrome (ACS). Aim of this review is to describe the pathophysiologic association between …

Blood glucose levels should be considered as a new vital sign indicative of prognosis during hospitalization

J Kesavadev, A Misra, B Saboo, SR Aravind… - Diabetes & Metabolic …, 2021 - Elsevier
Background and aims The measurement of vital signs is an important part of clinical work
up. Presently, measurement of blood glucose is a factor for concern mostly when treating …

Health-related quality of life and mortality in heart failure: the global congestive heart failure study of 23 000 patients from 40 countries

I Johansson, P Joseph, K Balasubramanian… - Circulation, 2021 - Am Heart Assoc
Background: Poor health-related quality of life (HRQL) is common in heart failure (HF), but
there are few data on HRQL in HF and the association between HRQL and mortality outside …

Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): health status analysis of a randomised, double-blind, placebo …

JA Spertus, JT Fine, P Elliott, CY Ho, I Olivotto, S Saberi… - The Lancet, 2021 - thelancet.com
Background Improving symptoms is a primary treatment goal in patients with obstructive
hypertrophic cardiomyopathy. Currently available pharmacological options for hypertrophic …

Comparison of New York Heart Association class and patient-reported outcomes for heart failure with reduced ejection fraction

SJ Greene, J Butler, JA Spertus, AS Hellkamp… - JAMA …, 2021 - jamanetwork.com
Importance It is unclear how New York Heart Association (NYHA) functional class compares
with patient-reported outcomes among patients with heart failure (HF) in contemporary US …

Cost-effectiveness of dapagliflozin for treatment of patients with heart failure with reduced ejection fraction

JT Parizo, JD Goldhaber-Fiebert, JA Salomon… - JAMA …, 2021 - jamanetwork.com
Importance In the Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure
(DAPA-HF) trial, dapagliflozin was shown to reduce cardiovascular mortality and …

Efficacy and safety of dapagliflozin in acute heart failure: Rationale and design of the DICTATE-AHF trial

ZL Cox, SP Collins, M Aaron, GA Hernandez… - American heart …, 2021 - Elsevier
Background Dapagliflozin, a sodium-glucose cotransporter-2 inhibitor, reduces
cardiovascular death and worsening heart failure in patients with chronic heart failure and …

Association of effective regurgitation orifice area to left ventricular end-diastolic volume ratio with transcatheter mitral valve repair outcomes: a secondary analysis of …

JA Lindenfeld, WT Abraham, PA Grayburn… - JAMA …, 2021 - jamanetwork.com
Importance Transcatheter mitral valve repair (TMVr) plus maximally tolerated guideline-
directed medical therapy (GDMT) reduced heart failure (HF) hospitalizations (HFHs) and all …

[HTML][HTML] Overview of the socio-economic consequences of heart failure

FP Hessel - Cardiovascular Diagnosis and Therapy, 2021 - ncbi.nlm.nih.gov
Heart failure (HF) is a frequent cause of morbidity and mortality worldwide. The prevalence
of HF increases, and in high-income countries, 1–2% of total healthcare expenditure is spent …

Diabetes mellitus and acute myocardial infarction: impact on short and long-term mortality

V Milazzo, N Cosentino, S Genovese… - Diabetes: from Research …, 2021 - Springer
Diabetes mellitus (DM) is an important risk factor for acute myocardial infarction (AMI) and a
frequent co-morbidity in patients hospitalized with AMI, being present in about 30% of cases …