[HTML][HTML] Activation or exhaustion of CD8+ T cells in patients with COVID-19

MS Rha, EC Shin - Cellular & molecular immunology, 2021 - nature.com
In addition to CD4+ T cells and neutralizing antibodies, CD8+ T cells contribute to protective
immune responses against SARS-CoV-2 in patients with coronavirus disease 2019 (COVID …

[HTML][HTML] T cell-oriented strategies for controlling the COVID-19 pandemic

JY Noh, HW Jeong, JH Kim, EC Shin - Nature Reviews Immunology, 2021 - nature.com
COVID-19 vaccination programmes are ongoing worldwide. Neutralizing antibodies are
thought to be key for host protection against COVID-19; however, strategies that focus only …

Beschlussentwurf der STIKO zur 4. Aktualisierung der COVID-19-Impfempfehlung und die dazugehörige wissenschaftliche Begründung

S Vygen-Bonnet, J Koch, C Bogdan, T Harder… - 2021 - edoc.rki.de
Die STIKO empfiehlt die Impfung gegen COVID-19 mit einem der beiden zugelassenen
mRNA-Impfstoffe (Comirnaty von BioNTech/Pfizer, COVID-19-Vaccine von Moderna) oder …

[HTML][HTML] T cell immunity to SARS-CoV-2

J Niessl, T Sekine, M Buggert - Seminars in immunology, 2021 - Elsevier
Exceptional efforts have been undertaken to shed light into the biology of adaptive immune
responses to SARS-CoV-2. T cells occupy a central role in adaptive immunity to mediate …

Hallmarks of immune response in COVID-19: Exploring dysregulation and exhaustion

A Mazzoni, L Salvati, L Maggi, F Annunziato… - Seminars in …, 2021 - Elsevier
One and half year following the occurrence of COVID-19 pandemic, significant efforts from
laboratories all over the world generated a huge amount of data describing the prototypical …

Durability of SARS-CoV-2–specific T-cell responses at 12 months postinfection

Z Lu, ED Laing, J Pena DaMata… - The Journal of …, 2021 - academic.oup.com
Background Characterizing the longevity and quality of cellular immune responses to severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enhances understanding of …

[HTML][HTML] Regulatory T cells as predictors of clinical course in hospitalised COVID-19 patients

S Caldrer, C Mazzi, M Bernardi, M Prato… - Frontiers in …, 2021 - frontiersin.org
Background The host immune response has a prominent role in the progression and
outcome of SARS-CoV-2 infection. Lymphopenia has been described as an important …

[HTML][HTML] The immune response to SARS-CoV-2 and variants of concern

E Torbati, KL Krause, JE Ussher - Viruses, 2021 - mdpi.com
At the end of 2019 a newly emerged betacoronavirus, severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), was identified as the cause of an outbreak of severe …

[HTML][HTML] Immunoinformatics analysis of sars-cov-2 orf1ab polyproteins to identify promiscuous and highly conserved t-cell epitopes to formulate vaccine for indonesia …

M Gustiananda, BP Sulistyo, D Agustriawan, S Andarini - Vaccines, 2021 - mdpi.com
SARS-CoV-2 and its variants caused the COVID-19 pandemic. Vaccines that target
conserved regions of SARS-CoV-2 and stimulate protective T-cell responses are important …

[HTML][HTML] Coronavirus disease (COVID-19) control between drug repurposing and vaccination: a comprehensive overview

AA Al-Karmalawy, R Soltane, A Abo Elmaaty… - Vaccines, 2021 - mdpi.com
Respiratory viruses represent a major public health concern, as they are highly mutated,
resulting in new strains emerging with high pathogenicity. Currently, the world is suffering …