A review of neutrophil extracellular traps (NETs) in disease: potential anti-NETs therapeutics

V Mutua, LJ Gershwin - Clinical reviews in allergy & immunology, 2021 - Springer
Activated neutrophils release neutrophil extracellular traps (NETs) in response to a variety of
stimuli. NETosis is driven by protein-arginine deiminase type 4, with the release of …

To trap a pathogen: neutrophil extracellular traps and their role in mucosal epithelial and skin diseases

C Domínguez-Díaz, GU Varela-Trinidad… - Cells, 2021 - mdpi.com
Neutrophils are the most abundant circulating innate immune cells and comprise the first
immune defense line, as they are the most rapidly recruited cells at sites of infection or …

Semi-Quantitative and Quantitative [18F]FDG-PET/CT Indices for Diagnosing Large Vessel Vasculitis: A Critical Review

O Gheysens, F Jamar, AWJM Glaudemans, H Yildiz… - Diagnostics, 2021 - mdpi.com
To confirm the diagnosis of large vessel vasculitis (LVV) with high accuracy, one of the
recommended imaging techniques is [18F] Fluoro-2-deoxy-d-glucose positron emission …

[HTML][HTML] Impact of modern antiviral therapy of chronic hepatitis B and C on clinical outcomes of liver disease

T Khoo, D Lam, JK Olynyk - World Journal of Gastroenterology, 2021 - ncbi.nlm.nih.gov
Chronic infections with the hepatitis B and C viruses have significant worldwide health and
economic impacts. Previous treatments for hepatitis C such as interferon and ribavirin …

Different disease endotypes in phenotypically similar vasculitides affecting small-to-medium sized blood vessels

EE Gill, ML Smith, KM Gibson, KA Morishita… - Frontiers in …, 2021 - frontiersin.org
Objectives: Chronic primary vasculitis describes a group of complex and rare diseases that
are characterized by blood vessel inflammation. Classification of vasculitis subtypes is …

Investigation of type I interferon responses in ANCA-associated vasculitis

I Batten, MW Robinson, A White, C Walsh… - Scientific Reports, 2021 - nature.com
Type I interferon (IFN) dysregulation is a major contributory factor in the development of
several autoimmune diseases, termed type I interferonopathies, and is thought to be the …

Expanded dengue syndrome with small–medium-vessel vasculitis: A case report

A Jose, M Dhar, PK Panda… - International journal of …, 2021 - journals.lww.com
Expanded dengue syndrome (EDS) is a well-described entity in the literature (after 2009),
with various new atypical presentations being identified each year. We report a case of 38 …

Clinical, laboratory and ultrasonographic interrelations in giant cell arteritis

C Soares, A Costa, R Santos, P Abreu, P Castro… - Journal of Stroke and …, 2021 - Elsevier
Objectives The diagnosis of giant cell arteritis (GCA) is based on the presence of clinical and
laboratory features. Color-duplex sonography (CDS) may supplant the limited sensitivity of …

Clinical features and outcomes of childhood polyarteritis nodosa: A single referral center experience

N Tekgöz, F Aydın, T Kurt, M Sezer, Z Tekin… - Modern …, 2021 - academic.oup.com
Objectives The aims of this study were to describe the clinical features, comorbidities and
outcome of systemic childhood polyarteritis nodosa (PAN) and to evaluate PAN-like …

ANCA status and renal parameters at month 12 post-diagnosis can help predict subsequent relapses in patients with granulomatosis with polyangiitis

LK Cho, S Carette, C Pagnoux - Seminars in Arthritis and Rheumatism, 2021 - Elsevier
Objective To determine the predictive value of disease characteristics at 12-month follow-up
after the diagnosis of GPA for subsequent relapses in a cohort of patients followed at a …