Nearly 80% of human chronic infections are caused due to bacterial biofilm formation. This
is the most leading cause for failure of medical implants resulting in high morbidity and …

Efficient conventional chemotherapy is limited by its nonspecific nature, which causes
severe systemic toxicity that can lead to patient discomfort and low therapeutic efficacy. The …

Despite significant advances in developing drugs to treat brain tumours, achieving
therapeutic concentrations of the drug at the tumour site remains a major challenge due to …

Giant vesicles (GVs) are closed bilayer membranes that primarily comprise amphiphiles with
diameters of more than 1 μm. Compared with regular vesicles (several tens of nanometers in …

We perform coarse-grained molecular dynamics simulations of bilayers composed of
various lipids and cholesterol at their different ratios. Simulations show that cholesterol-lipid …

The purpose of this thesis was to elucidate the effects of low-frequency (20 kHz), low-
intensity (100 mW/cm 2)(LFLI US) therapeutic ultrasound on macrophage behavior and …