Catalytic hairpin assembly (CHA) with advantages of high efficiency, flexible design, and
mild reaction condition is considered a promising molecular amplifier. Modified working …

Mycotoxin contamination in foods has posed serious threat to public health and raised
worldwide concern. The development of simple, rapid, facile, and cost‐effective methods for …

Early diagnosis and timely management of Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2) are the keys to preventing the spread of the epidemic and …

Fast and effective detection of epidemics is the key to preventing the spread of diseases. In
this work, we constructed a dual-wavelength ratiometric electrochemiluminescence (ECL) …

DNA walker machines, as one of the dynamic DNA nanodevices, have attracted extensive
interest in the field of analysis due to their inherent superiority. Herein, we reported a split …

Herein, an aptasensor based on Pb 2+ dependent DNAzyme driven DNA Walker with the
triple amplification signal strategy was developed for ultrasensitive detection of enrofloxacin …

Artificial molecular machines have found widespread applications ranging from fundamental
studies to biomedicine. More recent advances in exploiting unique physical and chemical …

Single-cell protein analysis is very important for understanding cellular heterogeneity and
single-cell biology. However, owing to the extremely low levels of some tumor-associated …

Despite the intrinsic programmability and flexible biological functions of DNA walkers, it
remains challenging for traditional DNA walkers to precisely control mechanical running …

A fast and simple Cas13a-based assay approach for direct detecting Ebola RNA in
unamplified samples is reported. The procedure (named Cas-Roller) is comprised of a 10 …