Role of neutrophil-lymphocyte ratio in the prognosis of acute ischaemic stroke after reperfusion therapy: A systematic review and meta-analysis

D Sharma, KJ Spring… - Journal of Central …, 2022 - journals.sagepub.com
Background Inflammation may mediate response to acute reperfusion therapy (RT) in acute
cerebral ischaemia. Neutrophil-lymphocyte ratio (NLR), an inflammatory biomarker, may …

[HTML][HTML] Glutamate scavenging as a neuroreparative strategy in ischemic stroke

O Kaplan-Arabaci, A Acari, P Ciftci… - Frontiers in …, 2022 - frontiersin.org
Stroke is the second highest reason of death in the world and the leading cause of disability.
The ischemic stroke makes up the majority of stroke cases that occur due to the blockage of …

Synergy of “Yiqi” and “Huoxue” components of QishenYiqi formula in ischemic stroke protection via lysosomal/inflammatory mechanisms

Y Wang, X Liu, W Zhang, S He, Y Zhang… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Ischemic stroke is one of the leading causes of mortality
and long-term disability worldwide. Currently, approved therapies of intravenous …

[HTML][HTML] Fatty acid-binding proteins: their roles in ischemic stroke and potential as drug targets

Q Guo, I Kawahata, A Cheng, W Jia, H Wang… - International journal of …, 2022 - mdpi.com
Stroke is among the leading causes of death and disability worldwide. However, despite
long-term research yielding numerous candidate neuroprotective drugs, there remains a …

Leukoaraiosis severity and post‐reperfusion outcomes in acute ischaemic stroke: a meta‐analysis

A Rastogi, R Weissert… - Acta Neurologica …, 2022 - Wiley Online Library
Objectives Severity of leukoaraiosis may mediate outcomes after reperfusion therapy in
acute ischaemic stroke (AIS) patients. However, the level of the association remains poorly …

PRMT8 attenuates cerebral ischemia/reperfusion injury via modulating microglia activation and polarization to suppress neuroinflammation by upregulating Lin28a

K Zheng, Y Zhang, C Zhang, W Ye, C Ye… - ACS Chemical …, 2022 - ACS Publications
Activation and polarization of microglia are involved in neuroinflammation and regulate
ischemic stroke-associated brain injury. Protein arginine methyltransferase 8 functions as a …

Non-invasive brain stimulation as therapeutic approach for ischemic stroke: insights into the (sub) cellular mechanisms

H Kemps, P Gervois, B Brone, R Lemmens… - Pharmacology & …, 2022 - Elsevier
Although spontaneous recovery can occur following ischemic stroke due to endogenous
neuronal reorganization and neuroplastic events, the degree of functional improvement is …

[HTML][HTML] EGCG protects the mouse brain against cerebral ischemia/reperfusion injury by suppressing autophagy via the AKT/AMPK/mTOR phosphorylation pathway

L Wang, M Dai, Y Ge, J Chen, C Wang… - Frontiers in …, 2022 - frontiersin.org
Stroke remains one of the leading reasons of mortality and physical disability worldwide.
The treatment of cerebral ischemic stroke faces challenges, partly due to a lack of effective …

[HTML][HTML] Repetitive xenon treatment improves post-stroke sensorimotor and neuropsychiatric dysfunction

MP Dandekar, X Yin, T Peng, S Devaraj… - Journal of Affective …, 2022 - Elsevier
Stroke is a life-changing event as stroke survivors experience changes in personality,
emotions and mood. We investigated the effect of xenon gas encapsulated in liposomes on …

Role of diabetes in stroke: Recent advances in pathophysiology and clinical management

SA Bradley, KJ Spring, RG Beran… - Diabetes/Metabolism …, 2022 - Wiley Online Library
The increasing prevalence of diabetes and stroke is a major global public health concern.
Specifically, acute stroke patients, with pre‐existing diabetes, pose a clinical challenge. It is …