Artificial cells: past, present and future

W Jiang, Z Wu, Z Gao, M Wan, M Zhou, C Mao… - ACS nano, 2022 - ACS Publications
Artificial cells are constructed to imitate natural cells and allow researchers to explore
biological process and the origin of life. The construction methods for artificial cells, through …

Hydrogels as functional components in artificial cell systems

ME Allen, JW Hindley, DK Baxani, O Ces… - Nature Reviews …, 2022 - nature.com
Recent years have seen substantial efforts aimed at constructing artificial cells from various
molecular components with the aim of mimicking the processes, behaviours and …

Protocells: Milestones and recent advances

I Gözen, ES Köksal, I Põldsalu, L Xue, K Spustova… - Small, 2022 - Wiley Online Library
The origin of life is still one of humankind's great mysteries. At the transition between
nonliving and living matter, protocells, initially featureless aggregates of abiotic matter, gain …

Endocytosis of coacervates into liposomes

T Lu, S Liese, L Schoenmakers, CA Weber… - Journal of the …, 2022 - ACS Publications
Recent studies have shown that the interactions between condensates and biological
membranes are of functional importance. Here, we study how the interaction between …

Vesicle-based artificial cells: materials, construction methods and applications

Y Lu, G Allegri, J Huskens - Materials horizons, 2022 - pubs.rsc.org
The construction of artificial cells with specific cell-mimicking functions helps to explore
complex biological processes and cell functions in natural cell systems and provides an …

Reaction–diffusion patterning of DNA-based artificial cells

A Leathers, M Walczak, RA Brady… - Journal of the …, 2022 - ACS Publications
Biological cells display complex internal architectures with distinct micro environments that
establish the chemical heterogeneity needed to sustain cellular functions. The continued …

Transient Out‐of‐Equilibrium Nucleic Acid‐Based Dissipative Networks and Their Applications

Z Li, J Wang, I Willner - Advanced Functional Materials, 2022 - Wiley Online Library
Dynamic, dissipative reactions play important roles in biological processes, and emulating
such biological processes by artificial circuits and networks is a challenging topic in the area …

Stimuli-responsive vesicles as distributed artificial organelles for bacterial activation

I Gispert, JW Hindley, CP Pilkington… - Proceedings of the …, 2022 - National Acad Sciences
Intercellular communication is a hallmark of living systems. As such, engineering artificial
cells that possess this behavior has been at the heart of activities in bottom-up synthetic …

Light‐Activated Membrane Transport in Polymeric Cell‐Mimics

S Cao, LC da Silva, K Landfester - Angewandte Chemie, 2022 - Wiley Online Library
Giant polymersomes are versatile and stable biomimetic compartments that are ideal for
building cell‐like systems. However, the transport of hydrophilic molecules across the …

Programmable spatial organization of liquid-phase condensations

J Li, Z Xu, M Zhu, C Zhao, X Wang, H Chen, X Liu… - Chem, 2022 - cell.com
Liquid-liquid phase separation (LLPS) is recognized as an important means of intracellular
compartmentalization in living cells. However, the spontaneous formation of hierarchical …