Psoriasis and cardiovascular disease risk in European and East Asian populations: evidence from meta-analysis and Mendelian randomization analysis

L Zhang, Y Wang, L Qiu, J Wu - BMC medicine, 2022 - Springer
Background Psoriasis has been linked to cardiovascular disease (CVD), including coronary
artery disease (CAD), myocardial infarction (MI), and heart failure (HF). However, available …

Psoriasis: an Immunogenetic perspective

A Kocaaga, M Kocaaga - Global medical genetics, 2022 - thieme-connect.com
Psoriasis is an erythematous-squamous dermatosis with a polygenic inheritance history.
Both environmental and genetic factors play a role in the etiology of the disease. Over the …

Endometriosis, psoriasis, and psoriatic arthritis: A prospective cohort study

HR Harris, KMN Korkes, T Li, M Kvaskoff… - American journal of …, 2022 - academic.oup.com
Endometriosis, psoriasis, and psoriatic arthritis (PsA) are chronic inflammatory disorders
whose etiologies remain poorly understood but may be correlated, as endometriosis has …

[HTML][HTML] Etiopathogenesis of psoriasis from genetic perspective: An updated review

F Babaie, M Omraninava, AM Gorabi… - Current …, 2022 - ncbi.nlm.nih.gov
Psoriasis is an organ-specific autoimmune disease characterized by the aberrant
proliferation and differentiation of keratinocytes, leading to skin lesions. Abnormal immune …

[HTML][HTML] Potential role of the epidermal differentiation complex in the pathogenesis of psoriasis

D Qin, L Ma, L Qin - Frontiers in Bioscience-Landmark, 2022 - imrpress.com
The skin is the largest barrier organ of the human body and serves to protect the internal
structure of the body from the harmful environment. The epidermis forms the outermost layer …

[HTML][HTML] Antimicrobial late cornified envelope proteins: The psoriasis risk factor deletion of LCE3B/C genes affects microbiota composition

H Niehues, DA van der Krieken, THA Ederveen… - Journal of Investigative …, 2022 - Elsevier
Late cornified envelope proteins are predominantly expressed in the skin and other cornified
epithelia. On the basis of sequence similarity, this 18-member homologous gene family has …

Multifactor dimensionality reduction reveals the effect of interaction between ERAP1 and IFIH1 polymorphisms in psoriasis susceptibility genes

C Zhang, Q Qin, Y Li, X Zheng, W Chen, Q Zhen… - Frontiers in …, 2022 - frontiersin.org
Background: Psoriasis is a common immune-mediated hyperproliferative skin dysfunction
with known genetic predisposition. Gene–gene interaction (eg, between HLA-C and ERAP1) …

Impact of chronic inflammation in psoriasis on bone metabolism

A Saalbach, M Kunz - Frontiers in Immunology, 2022 - frontiersin.org
Psoriasis is a chronic inflammatory disease of the skin and joints associated with several
comorbidities such as arthritis, diabetes mellitus and metabolic syndrome, including obesity …

Break on through: The role of innate immunity and barrier defence in atopic dermatitis and psoriasis

HC Hawerkamp, CMR Fahy, PG Fallon… - Skin Health and …, 2022 - Wiley Online Library
The human skin can be affected by a multitude of diseases including inflammatory
conditions such as atopic dermatitis and psoriasis. Here, we describe how skin barrier …

Clinical Overview of Psoriasis and Psoriatic Arthritis

F Valenzuela, R Flores - Textbook of Dermatologic Ultrasound, 2022 - Springer
Psoriasis is a chronic and immune-mediated inflammatory disease affecting the skin and
joints of approximately 2–3% of the world population, with a bimodal age distribution …