[HTML][HTML] Protein data bank: a comprehensive review of 3D structure holdings and worldwide utilization by researchers, educators, and students
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB),
funded by the United States National Science Foundation, National Institutes of Health, and …
funded by the United States National Science Foundation, National Institutes of Health, and …
The regulation of the protein interaction network by monoubiquitination
W Magits, AA Sablina - Current Opinion in Structural Biology, 2022 - Elsevier
The conjugation of a single ubiquitin or monoubiquitination acts as a versatile signal that
can have both degradative and non-degradative functions. The latter is of particular interest …
can have both degradative and non-degradative functions. The latter is of particular interest …
[HTML][HTML] A litmus test for classifying recognition mechanisms of transiently binding proteins
Partner recognition in protein binding is critical for all biological functions, and yet,
delineating its mechanism is challenging, especially when recognition happens within …
delineating its mechanism is challenging, especially when recognition happens within …
A fast microfluidic mixer enabling rapid preparation of homogeneous PEG and bicelle media for RDC in NMR analysis
Residual dipolar couplings (RDCs) are widely used in NMR for the investigation of protein
structure and dynamics. However, commonly used RDC media (eg, C 12 E 5/Hexanol/H 2 O …
structure and dynamics. However, commonly used RDC media (eg, C 12 E 5/Hexanol/H 2 O …
Panel of engineered ubiquitin variants targeting the family of human ubiquitin interacting motifs
G Veggiani, BP Yates, GD Martyn, N Manczyk… - ACS chemical …, 2022 - ACS Publications
Ubiquitin (Ub)-binding domains embedded in intracellular proteins act as readers of the
complex Ub code and contribute to regulation of numerous eukaryotic processes. Ub …
complex Ub code and contribute to regulation of numerous eukaryotic processes. Ub …
The native state conformational heterogeneity in the energy landscape of protein folding
The native structure of proteins is central to various functions performed by cells. A vital part
of the structure-function paradigm of proteins is their inherent flexibility and dynamics. The …
of the structure-function paradigm of proteins is their inherent flexibility and dynamics. The …
[HTML][HTML] The role of structural dynamics in the thermal adaptation of hyperthermophilic enzymes
Proteins from hyperthermophilic organisms are evolutionary optimised to adopt functional
structures and dynamics under conditions in which their mesophilic homologues are …
structures and dynamics under conditions in which their mesophilic homologues are …
Recognition and binding of RsmE to an AGGAC motif of RsmZ: insights from molecular dynamics simulations
A Ormazábal, G Pierdominici-Sottile… - Journal of Chemical …, 2022 - ACS Publications
CsrA/RsmE is a post-transcriptional regulator protein widely distributed in bacteria. It
impedes the expression of target mRNAs by attaching their 5′ untranslated region. The …
impedes the expression of target mRNAs by attaching their 5′ untranslated region. The …
[HTML][HTML] Elucidating the molecular basis of spontaneous activation in an engineered mechanosensitive channel
K Immadisetty, A Polasa, R Shelton… - Computational and …, 2022 - Elsevier
Mechanosensitive channel of large conductance (MscL) detects and responds to changes in
the pressure profile of cellular membranes and transduces the mechanical energy into …
the pressure profile of cellular membranes and transduces the mechanical energy into …
[HTML][HTML] Localising nuclear spins by pseudocontact shifts from a single tagging site
Ligating a protein at a specific site with a tag molecule containing a paramagnetic metal ion
provides a versatile way of generating pseudocontact shifts (PCSs) in nuclear magnetic …
provides a versatile way of generating pseudocontact shifts (PCSs) in nuclear magnetic …