Different mechanisms mediate the toxicity of RNA. Genomic retroviral mRNA hijacks infected
host cell factors to enable virus replication. The viral genomic RNA of the human …

This mini review focuses on the diagnosis and treatment of virus diseases using Crisper-Cas
technology. The present paper describes various strategies involved in diagnosing diseases …

Viral DNA and RNA polymerases are two kinds of very important enzymes that synthesize
the genetic materials of the virus itself, and they have become extremely favorable targets for …

The azaindole (AI) framework continues to play a significant role in the design of new
antiviral agents. Modulating the position and isosteric replacement of the nitrogen atom of AI …

Abstract Introduction In Mexico, HIV genotyping is performed in people living with HIV
(PLWH) failing their first-line antiretroviral (ARV) regimen; it is not routinely done for all …

Apolipoprotein B mRNA-editing catalytic polypeptide-like 3 family members (APOBEC3s)
are host restriction factors that inhibit viral replication. Viral infectivity factor (Vif), a human …

Background and Objectives: DNA-based therapeutic vaccines have been proposed as a
promising strategy for the treatment of established HIV infections. However, these vaccines …

Retroviral proteases are essential enzymes for viral replication and drive changes within the
cellular proteome. While several studies have demonstrated that protease (PR) enzymes …

La latence du virus de l'immunodéficience humaine (VIH) est actuellement un obstacle
majeur à l'éradication des cellules infectées. En effet, en état de latence, le VIH se réplique …

[1.] Montaner JSG, Lima VD, Harrigan PR, et al. Expansion of HAART coverage is
associated with sustained decreases in HIV/AIDS morbidity, mortality and hiv transmission …