Spinal microglia and astrocytes: two key players in chronic visceral pain pathogenesis

JY Long, XJ Wang, XY Li, XH Kong, G Yang… - Neurochemical …, 2022 - Springer
Chronic visceral pain (CVP) is one of the common symptoms of many diseases triggered by
underlying diseases of the internal organs of the human body. Its causes include vascular …

The opioid epidemic from the acute care hospital front line

PE Macintyre - Anaesthesia and Intensive Care, 2022 - journals.sagepub.com
Prescription opioid use has risen steeply for over two decades, driven primarily by advocacy
for better management of chronic non-cancer pain, but also by poor opioid stewardship in …

Pharmaceutical opioid poisonings in Victoria, Australia: rates and characteristics of a decade of emergency department presentations among nine pharmaceutical …

T Lam, J Hayman, J Berecki‐Gisolf, P Sanfilippo… - …, 2022 - Wiley Online Library
Background and aims Pharmaceutical opioids are a significant contributor to the global
'opioid crisis', yet few studies have comprehensively distinguished between opioid types. We …

Antinociceptive activities and mechanism of action of Cepharanthine

XY Wei, JD Long, JR Chai, J Chen, JP Gao… - Biochemical and …, 2022 - Elsevier
Cepharanthine is an alkaloid that isolated from Stephania cepharantha Hayata, however, its
analgesic properties are unclear and the molecular targets that mediating Cepharanthine …

Comparing opioid types in the persistence of opioid use following surgical admission: a study protocol for a retrospective observational linkage study comparing …

T Lam, N Biggs, T Xia, J Evans, J Stevens… - BMJ open, 2022 - bmjopen.bmj.com
Introduction Each year, an estimated two million Australians commence opioids, with 50 000
developing longer-term (persistent) opioid use. An estimated 3%–10% of opioid-naïve …

[HTML][HTML] Characterizing the Experience of Tapentadol Nonmedical Use: Mixed Methods Study

SK Vosburg, T Dailey-Govoni, J Beaumont… - JMIR Formative …, 2022 - formative.jmir.org
Background The prevalence of abuse, diversion, and web-based endorsement of tapentadol
(extended-release [ER], immediate-release [IR]) has been characterized as low compared …

[HTML][HTML] Protocol: Comparing opioid types in the persistence of opioid use following surgical admission: a study protocol for a retrospective observational linkage study …

T Lam, N Biggs, T Xia, J Evans, J Stevens, M da Gama… - BMJ Open, 2022 - ncbi.nlm.nih.gov
Introduction Each year, an estimated two million Australians commence opioids, with 50 000
developing longer-term (persistent) opioid use. An estimated 3%–10% of opioid-naïve …

Predictors of older adults' chronic pain in the context of opioid adverse drug events

DD McDonald, SJ Walsh - Journal of the American Association of …, 2022 - journals.lww.com
Background: Factors predictive of chronic pain in older adults could help focus prevention
and treatment efforts for those most at risk of chronic pain. Purpose: The objective of the …