Chronic renin-angiotensin System Activation induced neuroinflammation: common mechanisms underlying hypertension and dementia?

S Tran, S Kuruppu… - Journal of Alzheimer's …, 2022 - content.iospress.com
Hypertension is a major risk factor for the pathogenesis of vascular dementia and
Alzheimer's disease. Chronic activation of the renin-angiotensin system (RAS) contributes …

Potential role of drug repositioning strategy (DRS) for management of tauopathy

MO Zaki, DA Elsherbiny, M Salama, SS Azab - Life sciences, 2022 - Elsevier
Tauopathy is a term that has been used to represent a pathological condition in which
hyperphosphorylated tau protein aggregates in neurons and glia which results in …

Dietary Alterations in Impaired Mitochondrial Dynamics Due to Neurodegeneration

GM Ashraf, S Chatzichronis, A Alexiou… - Frontiers in Aging …, 2022 - frontiersin.org
Alzheimer's disease is still an incurable disease with significant social and economic impact
globally. Nevertheless, newly FDA-approved drugs and non-pharmacological techniques …